Marine microbiomes are an untapped resource of microorganisms and natural
bioactive compounds that constitute a source of candidates for the development
of pharmaceuticals and crop protection agents. Computational integration of
different types of omics data, such as genomics and metabolomics profiles,
constitutes a promising avenue to uncover this potential. In this project,
based on foundational work by our group, you will implement innovative
computational approaches to chart the biosynthetic diversity found in
metagenome sequences from marine microbiomes, connect the predicted
biosynthetic gene clusters to metabolites, and use a combination of genomic
and metabolomic data to help elucidate chemical (sub)structures. You will
construct a database of natural product-acting enzymes from experimentally
verified biosynthetic pathways and use this as a basis to computationally
predict chemical transformations encoded by newly identified biosynthetic gene
clusters, in order to match these to their chemical products observed in the
metabolome. Computational integration of genomic, mass-spectrometric and NMR
data will be used to facilitate structure approximation of biosynthetic
products, which can be used for dereplication, prioritization, and finally
You will work closely with PhD students and postdocs appointed within the same
consortium around Europe, which will make it possible to elucidate the
structures of the chemical products and confirm the ecological roles of the
pathways you identify. In the end, the research is projected to lead to
fundamental new insights into microbe-microbe and host-microbe interactions,
and may provide leads for the development of novel pharmaceuticals and
crop/aquaculture protection solutions.
We are looking for an ambitious, enthusiastic team player and result-driven
an excellent academic record (PhD) in bioinformatics or computational
affinity with (microbial) metabolism and omics analyses;
demonstrable expertise in working with genomic and/or metabolomic data;
proven proficiency in programming (in, e.g., Python);
at least basic to intermediate statistical and mathematical skills;
excellent oral and written communication skills in English.
Conditions of employment
Wageningen University & Research offers excellent terms of employment. A few
highlights from our Collective Labour Agreement include:
sabbatical leave, study leave, and paid parental leave;
working hours that can be discussed and arranged so that they allow for
the best possible work-life balance;
the option to accrue additional holiday hours by working more, up to 40
hours per week;
there is a strong focus on vitality and you can make use of the sports
facilities available on campus for a small fee;
a fixed December bonus of 8.3%;
excellent pension scheme.
In addition to these first-rate employee benefits, you will of course receive
a good salary. Depending on your experience, we offer a competitive salary of
between €3270,- and €4207.- for a full-time working week of 38 hours, in
accordance with theCollective Labour Agreements for Dutch Universities (CAO-
NU)(scale 10). The position is full-time (38 hours/week), for a period of
Wageningen University & Research encourages internal advancement opportunities
and mobility with an internal recruitment policy. There are plenty of options
for personal initiative in a learning environment, and we provide excellent
training opportunities. We are offering a unique position in an international
environment with a pleasant and open working atmosphere.
You are going to work at the greenest and most innovative campus in Holland,
and at a university that has been chosen as the "Best University" in the
Netherlands for the 16th consecutive time.
Coming from abroad
Wageningen University & Research is the university and research centre for
life sciences. The themes we deal with are relevant to everyone around the
world and Wageningen, therefore, has a large international community and a lot
to offer to international employees. Applicants from abroad moving to the
Netherlands may qualify for a special tax relief, known as the 30% ruling. Our
team of advisors on Dutch immigration procedures will help you with the visa
application procedures for yourself and, if applicable, for your family.
Feeling welcome also has everything to do with being well informed. Wageningen
University & Research's International Community page contains practical
information about what we can do to support international employees and
students coming to Wageningen. Furthermore, we can assist you with any
additional advice and information about helping your partner to find a job,
housing, schooling, and other issues.
Wageningen University & Research
Wageningen University & Research
The mission of Wageningen University and Research is "To explore the potential
of nature to improve the quality of life". Under the banner Wageningen
University & Research, Wageningen University and the specialised research
institutes of the Wageningen Research Foundation have joined forces in
contributing to finding solutions to important questions in the domain of
healthy food and living environment.
With its roughly 30 branches, 6.800 employees and 12.900 students, Wageningen
University & Research is one of the leading organisations in its domain. An
integrated approach to problems and the cooperation between various
disciplines are at the heart of Wageningen's unique approach. WUR has been
named Best Employer in the Education category for 2019-2020.
Read the 5 reasons why your future collaegues enjoy working at WUR and watch
this video to get an idea of our green campus!
We will recruit for the vacancy ourselves, so no employment agencies please.
However, sharing in your network is appreciated.
For more information about this position, please contact dr. Marnix Medema
(email@example.com) or Justin van der Hooft
(firstname.lastname@example.org).For more information about the procedure, please
Do you want to apply?
You can apply directly using the apply button on the vacancy page on our
website which will allow us to process your personal information with your
This vacancy will be listed up to and including 7 October 2021.
In this first round please only send your resume and motivation letter. Any
other documents will not be taken into consideration at this stage.
Wageningen University & Research (WUR) employs a large number of people with
very different backgrounds and qualities, who inspire and motivate each other.
We want every talent to feel at home in our organisation and be offered the
same career opportunities. We therefore especially welcome applications from
people who are underrepresented at WUR. For more information please go to our
inclusivity page. A good example of how WUR deals with inclusiveness can be
read on the page working at WUR with a functional impairment.