Postdoc (M/F) In Rna Biophysics And Structural Biology

Universities and Institutes of France

France

September 23, 2022

Description

  • Organisation/Company: CNRS
  • Research Field: Biological sciences › Biological engineering Chemistry › Biochemistry Physics › Biophysics
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 23/09/2022 23:59 - Europe/Brussels
  • Location: France › STRASBOURG
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 35
  • Offer Starting Date: 01/11/2022
  • - large-scale RNA production and purification - RNA chemical probing - biophysics (fluorescence, spectroscopy, mass spectrometry, calorimetry, biosensors) - structural biology (X-ray crystallography, cryo-EM, NMR) - molecular modeling

    The candidate will be in charge of studying the structure of a long non-coding RNA involved in solid cancers, as well as characterizing its interaction with potential partners (proteins, RNPs) in order to identify its mechanism of action and ways to interfere with its biological role.

    The laboratory "Architecture and Reactivity of RNA", CNRS UPR 9002, is a multidisciplinary laboratory where the research themes developed are related to the biology of the RNA world. The candidate will be hosted in the team "Structure and Dynamics of Biomolecular Machines" which includes 6 CNRS and INSERM researchers and 3 CNRS engineers as well as students and interns. The team has a strong expertise in biophysics and structural biology of RNA (NMR, crystallography and cryoEM) and relies on a biophysics platform available in the laboratory as well as on an easy access to the large infrastructures needed in structural biology.

    Translated with www. DeepL.com/Translator (free version)

    Eligibility criteria

    - good knowledge of RNA biology - working knowledge of the Linux operating system - expertise in RNA solution mapping - expertise in biophysics - expertise in structural biology (NMR or X-ray crystallography or cryoEM)

    Web site for additional job details

    https: // emploi.cnrs.fr/Offres/CDD/UPR9002-ERIENN-003/Default.aspx

    Required Research Experiences
  • RESEARCH FIELD
  • Chemistry › Biochemistry

  • YEARS OF RESEARCH EXPERIENCE
  • None

  • RESEARCH FIELD
  • Physics › Biophysics

  • YEARS OF RESEARCH EXPERIENCE
  • None

  • RESEARCH FIELD
  • Biological sciences › Biological engineering

  • YEARS OF RESEARCH EXPERIENCE
  • None

    Offer Requirements
  • REQUIRED EDUCATION LEVEL
  • Chemistry: PhD or equivalent

    Physics: PhD or equivalent

    Biological sciences: PhD or equivalent

  • REQUIRED LANGUAGES
  • FRENCH: Basic

    Contact Information
  • Organisation/Company: CNRS
  • Department: Architecture et Réactivité de l'ARN
  • Organisation Type: Public Research Institution
  • Website: https:// www-ibmc.u-strasbg.fr/arn/
  • Country: France
  • City: STRASBOURG
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