Postdoc in the project “Human milk oligosaccharides’ impact on maturation of the gut microbiota”

Technical University of Denmark


July 1, 2021


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Postdoc in the project “Human milk oligosaccharides' impact on maturation of

the gut microbiota”

DTU Bioengineering

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Thursday 10 Jun 21

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Apply no later than 1 July 2021 Apply for the job at DTU Bioengineering by completing the following form.

A three year postdoc position is available in the Protein Glycoscience and Biotechnology group, Protein Chemistry and Enzyme Technology section at the Department of Biotechnology and Biomedicine. A major focus of this group, headed by Prof. Maher Abou Hachem, is to perform impactful work on understanding the molecular basis of glycan utilisation by key members of the human gut microbiota and to develop biotechnological application for enzymes from this ecological niche.

The project's goal is to bring insight into the role of human milk oligosaccharides (HMOs) in the maturation of the human gut microbiota.

Responsibilities and tasks Your tasks will be:

  • Design and perform experiments to understand the scope and the mechanisms of HMO utilisation by distinct groups of the human gut microbiota
  • In collaboration with the PhD student and the project collaboration partners map the HMO utilisation potential in silico and express and characterize key proteins involved in this metabolic facet
  • Design anaerobic growth experiments to evaluate growth preferences of diverse microbiota members on complex and defined relevant substrates
  • Determine the three-dimensional crystal structures of key protein players identified in the project
  • Take part in scientific, dissemination and collaboration activities related to the project and the research group as well co-supervision of students at different levels
  • Qualifications Candidate should have a PhD within Protein chemistry. Ideal candidate profile:

  • Strong background in enzymology and protein biophysical chemistry
  • Experience in carbohydrate chemistry and carbohydrate active enzymes
  • Experience in anaerobic microbiology, and growth and competition assay of various diverse strict anaerobes of the human gut microbiota.
  • Excellent scientific track record of original high impact publications of relevance to project
  • We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

    Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

    You can read more about career paths at DTU here .

    The position is for 3 years.

    Further information Further information may be obtained from Maher Abou Hachem, tel.: +45 4525 2732, e-mail:

    You can read more about the Department of Biotechnology and Biomedicine at www. and about the Protein Glycoscience and Biotechnology group https: // www. sections/section-for-protein-chemistry-and-enzyme- technology/proteinglycoscience

    If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

    Application procedure Please submit your online application no later than 1 July 2021 (Danish time).

    Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Diploma (MSc/PhD)
  • List of publications
  • Applications and enclosures received after the deadline will not be considered.

    All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

    Technology for people DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN's 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.