Postdoc in Nanocarrier Drug Delivery

Technical University of Denmark

Denmark

February 6, 2022

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Postdoc in Nanocarrier Drug Delivery

DTU Health Tech

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Thursday 06 Jan 22

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Apply no later than 6 February 2022 Apply for the job at DTU Health Tech by completing the following form.

DTU Health Tech is looking for a highly motivated postdoctoral researcher to join the ocular drug delivery research group, led by Assoc. Prof. Andrew Urquhart, to work on light driven nanocarrier transport within the eye.

The Job We are exploring the potential of laser light as a mechanism to drive nanocarriers to the retina and optic nerve. This ambitious and challenging interdisciplinary project is a collaboration between Prof. Anders Kristen (optofluidics), Assoc. Prof Jonas Pedersen (physical modelling) and Assoc. Prof. Andrew Urquhart (ocular drug delivery). We believe that our technology has the potential to revolutionize the treatment of vision threatening diseases such as diabetic retinopathy, glaucoma and age-related macular degeneration. The successful candidate will join the ocular drug delivery research group working predominantly on nanocarrier design, synthesis and characterization. There will be interdisciplinary research aspects involving optofluidics, ex vivo eye models and modelling. As such, the successful candidate will possess an interdisciplinary mindset with a personal drive to learn new fields of scientific research. This position holds a unique opportunity to drive a new technology that holds considerable potential in ocular drug delivery research and patient healthcare.

Responsibilities Your overall focus will be the design, synthesis and characterization of lipid and protein based nanocarriers. Nanocarriers will be labelled with appropriate markers (e.g. fluorophores) and loaded with small molecule drugs or biologics. You will work with collaborators and their corresponding research teams. Your primary tasks will be:

  • Design, synthesis, functionalization and characterization of lipid and protein based nanocarriers.
  • Conduct data analysis and disseminate results in peer reviewed research articles.
  • Provide input in the evaluation of project data.
  • Clearly communicate, document and store results obtained.
  • Support optofluidic, ex vivo eye models and modelling experiments. This will involve providing samples, working alongside collaborators (e.g. in data collection) and potentially learning to perform experiments in these areas.
  • Co-supervise BSc, MSc and PhD students in the ocular drug delivery group.
  • Qualifications You must hold a PhD degree (or equivalent) in a physical science (e.g. chemistry, biophysics, pharmaceutics etc.) with a focus on nanocarrier drug delivery systems. You will have the following qualifications:

  • Extensive knowledge of lipidic and protein based nanocarriers.
  • Experience with lipidic and/or protein nanocarrier synthesis and functionalization (e.g. antibody conjugation, fluorophore conjugation etc.)
  • Experience with liquid chromatography and dynamic light scattering techniques.
  • Experience within ocular drug delivery, tissue handling and/or mass spectrometry is an advantage.
  • We offer DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

    Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 2 years.

    You can read more about career paths at DTU here .

    Further information Further information may be obtained from Associate Professor Andrew Urquhart (anur@dtu.dk, +45 4525 8169).

    You can read more about DTU Health Tech at www. healthtech.dtu.dk/english and the Ocular Drug Delivery Group here.

    If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

    Application procedure Your complete online application must be submitted no later than 6 February 2022 (Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Academic Diplomas (MSc/PhD)
  • List of publications
  • Applications received after the deadline will not be considered.

    All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

    DTU Health Tech DTU Health Tech engages in research, education and innovation based on technical and natural science for the healthcare sector. The healthcare sector is a globally expanding market with demands for the most advanced technical solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Tech's expertise spans imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 130 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

    Technology for people DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN's 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 12,900 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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