Postdoc In Biochemistry

Universities and Institutes of France
February 15, 2023
Contact:N/A
Offerd Salary:Negotiation
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Contract Type:Temporary
Working Time:Full time
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  • Organisation/Company: Ecole supérieure de physique et de chimie industrielles de la ville de Paris
  • Research Field: Biological sciences › Biological engineering Chemistry Physics
  • Researcher Profile: Recognised Researcher (R2)
  • Application Deadline: 15/02/2023 00:00 - Europe/Brussels
  • Location: France › Paris
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 35
  • Offer Starting Date: 01/04/2023
  • Eu Research Framework Programme: H2020 / ERC
  • Reference Number: ERC-2020-COG (GA 101002075)
  • A central question in the origin of life is how evolution could have emerged in physical-chemical systems. RNA is an experimental model for the prebiotic world because RNA is both an information carrier and a catalyst. RNAs derived from group I introns have been shown to self-reproduce from smaller fragments, recombine other RNAs, and produce novel ribozymes. Therefore, RNA is a highly promising model to build an artificial reactions networks capable of evolution. However, a system made of RNA and capable of evolution remains to be discovered.

    The project aims to build novel in vitro RNA ribozymes capable of self- reproduction. We will use high-throughput screens of catalytic activities, directed evolution, rational design, in close collaboration with computer modelling.

    Web site for additional job details

    https: // www. lbe.espci.fr

    Required Research Experiences
  • RESEARCH FIELD
  • Biological sciences

  • YEARS OF RESEARCH EXPERIENCE
  • 1 - 4

    Offer Requirements
  • REQUIRED EDUCATION LEVEL
  • Biological sciences: PhD or equivalent

  • REQUIRED LANGUAGES
  • ENGLISH: Excellent

    Skills/Qualifications

    Given the highly interdisciplinary nature of these projects, candidates from diverse backgrounds will be considered: Molecular biology, RNA biochemistry, Experimental evolution.

    Specific Requirements

    In any case, the candidate should have a strong motivation to learn novel techniques, concepts and to team work in an interdisciplinary environment.

    Contact Information
  • Organisation/Company: Ecole supérieure de physique et de chimie industrielles de la ville de Paris
  • Organisation Type: Public Research Institution
  • Website: https: // www. espci.fr/fr/
  • Country: France
  • City: Paris
  • Postal Code: 75005
  • Street: 10 rue Vauquelin
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