Umeå University, Faculty of Medicine
Umeå University is one of Sweden's largest institutions of higher
education with over 35,000 students and 4,200 faculty and staff. We are
characterised by world-leading research in several scientific fields and a
multitude of educations ranked highly in international comparison. Umeå
University is also the site of the pioneering discovery of the CRISPR-Cas9
genetic scissors - a revolution in genetic engineering that has been awarded
the Nobel Prize in Chemistry.
At Umeå University, everything is nearby. Our cohesive campus environment
makes it easy to meet, collaborate and exchange knowledge, which promotes a
dynamic and open culture where we rejoice in each other's successes.
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The Faculty of Medicine, which consists of 13 departments, is responsible for
biomedical research and courses in the field of nursing and health care and
has an extensive research and graduate education in more than 80 subjects.
The Department of Odontology conducts teaching in the dental program, dental
hygienist program and dental technician program as well as research in mouth,
face and jaws. Today there are approximately 70 employees who work in
education, research and administration within the department. Here is an
opportunity to apply for a position as a postdoctoral fellow in oral
immunology to in detail study the role of the immune system in periodontitis
and general mechanisms that control inflammation-driven bone resorption. The
employment is limited to two years and is full-time based in Umeå. Access
2022-10-01, or by agreement. The application deadline is October 1st.
Inflammation of the gums (gingivitis) is very common and is caused by
bacteria found in connection with the teeth and gums. Due to factors that are
not fully understood, only some develop periodontitis, which means that the
gingivitis process turns into an extensive destruction of the collagen-rich
connective tissue and bone that constitute the attachment of the teeth. Bone
loss is not only seen in periodontitis, but also in, for example, peri-
implantitis and rheumatoid arthritis. In these diseases, bone loss is
considered an irreversible condition that risks impairing the function of
teeth, implants and joints. However, the molecular mechanisms behind
inflammatory bone loss are not fully mapped. Our hypothesis is that there are
common molecules that cause inflammation-driven bone loss in individuals who,
due to genetic factors, are more susceptible to disease. The overall aim of
the project is to identify markers to detect who is at risk of suffering from
inflammatory bone loss, such as periodontitis, before the bone breakdown
begins. With our research, we also want to discover new osteoimmunological
principles that could be attacked with targeted therapy to slow down or
prevent inflammation-driven bone loss.
In our research group, you are expected to contribute with your own ideas to
the research project we are conducting. You must be able to work independently
and have documented solid experience in experimental research. Your role will
be to plan and carry out experiments under the supervision of the research
group leaders, as well as to support more junior researchers, PhD students and
students in adjacent projects with overlapping goals and methods. The work
includes a lot of challenging laboratory work, but also requires independent
work with project design, data analysis, presentation of results at scientific
meetings, and writing of publications.
More specifically, you will perform flow cytometric analysis of bone marrow
cells as well as different lymphocyte populations in gingival tissue. You will
isolate and culture bone and connective tissue cells, work with experiments in
a number of cell culture systems, and perform geno- and phenotype
characterization with various techniques. Work in periodontitis, peri-
implantitis and arthritis animal models may also be relevant.
Eligible to be employed as a postdoctoral fellow is someone who has
completed a doctoral degree, or a foreign degree deemed to be equivalent to a
doctoral degree, in the subject of medical/biomedical research (e.g.
immunology, biochemistry, molecular biology or biomedicine). This eligibility
requirement must be met at the latest at the time when the employment decision
We are looking for a driven and highly motivated employee who has documented
experience in molecular biology research, flow cytometry, cell culture and
gene expression and protein analyses. The applicant must have good knowledge
of English, both spoken and written. Great emphasis will be placed on personal
Since employment as a postdoctoral fellow is a merit-based position for
junior researchers, we primarily target those who have a doctoral degree that
is no older than three years from the last date of application. If there are
special reasons, it can be considered as having completed a doctoral degree
earlier. With special reasons is meant leave due to illness, parental leave,
clinical duty, trust assignments in trade unions or other similar
circumstances, as well as duty/assignment relevant to the subject area.
Documented experience in cultivating macrophages/monocytes/osteoclasts but
also stromal cells such as fibroblasts and osteoblasts is meritorious for the
position. Previous experience of postdoctoral work is meritorious for the
position. Documented experience of independently performing flow cytometry
assays (including design of new panels), as well as experience
characterizing lymphocyte populations is a strong track record.
As work in experimental animal models is included in the duties, such
experiences are considered meritorious.
The applicant should have a good ability to work clearly and in a structured
manner and report the results obtained. Great importance is placed on the
applicant's interest in the subject area and suitability for the project.
Knowledge of Swedish is seen as meritorious.
More about the employment
The employment is a temporary, full-time employment for two years according
to the terms of the agreement on temporary employment as a postdoctoral
researcher from 1 October 2022.
More information about the group's research can be read below:
Link to BIG-PL: https: // www. umu.se/forskning/projekt/den-vavnadsforstorande-
Link to EK: https: // www. umu.se/wallenberg-centrum-for-molecular-
The application must contain:
A brief description of your research interests, scientific merits and
justification as to why you are interested in employment.
List of publications
Degree certificate from postgraduate education and other relevant degrees
Contact information for two reference persons
The application must be written in Swedish or English. The application must be
made via our e-recruitment system Varbi and received no later than October 1,
For questions about the employment, please contact Professor Pernilla Lundberg
firstname.lastname@example.org, or assistant university lecturer Elin Kindstedt
Welcome with your application!
Umeå University strives to offer an equal environment where open dialogue
between people with different backgrounds and perspectives lay the foundation
for learning, creativity and development. We welcome people with different
backgrounds and experiences to apply for the current employment.
We kindly decline offers of recruitment and advertising help.
Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment By agreement
Salary Monthly salary
Number of positions 1
Working hours 100 %
County Västerbottens län
Reference number AN 2.2.1-1344-22
Last application date 01.Oct.2022 11:59 PM CEST
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