Post-Doctoral Researcher

Universities and Institutes of France

France

November 1, 2022

Description

  • Organisation/Company: Nantes Université
  • Research Field: Chemistry › Biochemistry Pharmacological sciences › Pharmacognosy
  • Researcher Profile: First Stage Researcher (R1) Recognised Researcher (R2)
  • Application Deadline: 01/11/2022 12:00 - Europe/Brussels
  • Location: France › Nantes
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 38b2
  • Offer Starting Date: 01/12/2022
  • This position is entirely dedicated to the "HALO-CAT" project, funded by the National Research Agency (https: // anr.fr/Projet-ANR-21-CE44-0003) and will consist of producing, purifying, analyzing and identifying natural halogenated molecules using metabolomics tools (chemometrics, molecular networks , etc.) for their detection, conventional methods of extractive chemistry for their targeted purification, but also by biocatalysis approaches based on halogenation enzymes purified from marine fungi. In addition, the structures of the molecules obtained will be elucidated and their activity evaluated on different biological targets, more particularly on a panel of bacterial and fungal strains of therapeutic interest. Depending on the progress of the project and the molecules obtained, the elucidation of the biosynthetic pathways of these compounds, and more particularly the halogenation mechanisms involved, will be investigated via molecular biology and genetic engineering approaches in collaboration with partner teams from the project.

    The recruited person will also participate in the upkeep and maintenance of the analytical park, the management of the budget and consumables dedicated to the project as well as the writing of reports, publications and the dissemination and valuation of the results.

    Benefits

    Salary: €2,271 gross per month according to the Nantes Université contract management charter for non-tenured employees

    Eligibility criteria

    Training and/or qualification: PhD (preferably in chemistry but other applications will be considered)

    Selection process

    1st phase : selection of candidates based on CV, letters from 2 references and motivation letter

    2nd phase : auditions of the candidates by videoconferences for selected candidates

    Additional comments

    Previous experience welcome for the position: Phytochemistry, Biocatalysis and/or biotransformation, Metabolomics

    Required Research Experiences
  • RESEARCH FIELD
  • Pharmacological sciences › Pharmacognosy

  • YEARS OF RESEARCH EXPERIENCE
  • 1 - 4

    Offer Requirements
  • REQUIRED EDUCATION LEVEL
  • Chemistry: PhD or equivalent

  • REQUIRED LANGUAGES
  • ENGLISH: Excellent

    Skills/Qualifications
  • General, theoretical or disciplinary knowledge:
  • - Mass spectrometry

    - Chromatographic methods

    - Nuclear magnetic resonance

    - Microbiological cultures

    - Writing scientific reports

    - Expression in English language

  • Operational skills:
  • - Extraction, purification and isolation of natural molecules

    - HPLC-MS analyses

    - Desired: Data processing and analysis via dedicated bioinformatics tools (molecular networks and/or metabolomics tools)

  • Soft skills:
  • - Autonomy

    - Team work

    - Dynamism

    - Specialized communication and popularization

    Contact Information
  • Organisation/Company: Nantes Université
  • Department: Equipe M3 - Metabolites du Microbiome Marin - UR2160 ISOMer - Institut des Substances et Organismes de la Mer
  • Organisation Type: Research Laboratory
  • Website: https: // isomer.univ-nantes.fr/
  • E-Mail: secretariat.isomer@univ-nantes.fr
  • Country: France
  • City: Nantes
  • Postal Code: 44000
  • Street: Chemin de la Houssinière
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