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Post-Doctoral Researcher - High-Throughput Lipidomics
80%-100%, Zurich, fixed-term
The Institute of Molecular Systems Biology at ETH Zurich is inviting
applications for a Postdoctoral position in the laboratory of Professor Dr
The group of Dr Zamboni researches the function and regulation of metabolism.
In particular, the group is attracted by
systems in which metabolism or metabolites drive phenotypic
problems of biomedical relevance, and
cases that are especially complex or technically challenging
To tackle such problems, the group is largely devoted to the development of
novel approaches for metabolomics, lipidomics, and 13C metabolic flux
analysis, data processing and integration.
The Zamboni lab is tightly embedded in national initiatives on personalized
health, i.e. PHRT (www. sfa-phrt.ch). It hosts the PHRT Clinical Metabolomics
Analysis Center (CMAC), which aims at providing cutting-edge metabolomics
and lipidomics analysis to drive clinical research. While CMAC is productively
contributing to numerous projects with tens of thousands of measurements per
year, the PHRT is entering its second term (2022-2025) with novel aims. To
tackle emerging trends, the lab is seeking several specialists with
complementary expertise and interest. In the realm of lipidomics, these
activities entail achieving a finer structural characterization while
preserving sample throughput, expanding the toolbox of isotopic tracing for
quantification of lipid levels and fluxes, disentangling lipid metabolism and
trafficking across cellular organelles.
contribute to the development of innovative gas phase separation and
fragmentation lipidomics methods
contribute to building a full service portfolio for clinical and
conduct lipidomics MS analyses on various systems (TOFs and Orbitraps, LC
participate in instrument maintenance.
synergize with team members, collaborators, and vendors.
a doctoral degree in analytical chemistry or a related field.
ample experience in analytical lipidomics from sample preparation to data
sound knowledge of lipid chemistry and biochemistry.
excellent general technical skills in LC-HRMS, with hands-on experience in
experience with performing and interpreting isotopic tracing experiments
is an additional asset.
ETH Zurich is one of the world's leading universities specialising in science
and technology. We are renowned for our excellent education, cutting-edge
fundamental research and direct transfer of new knowledge into society. Over
30,000 people from more than 120 countries find our university to be a place
that promotes independent thinking and an environment that inspires
excellence. Located in the heart of Europe, yet forging connections all over
the world, we work together to develop solutions for the global challenges of
today and tomorrow.
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We look forward to receiving your online application with the following
A motivation letter stating own visions and specifying any past experience
that is aligned with the job profile
Name and contact of two referees
Please note that we exclusively accept applications submitted through our
online application portal. Applications via email or postal services will not
Further information about the Institute of Molecular Systems Biology can be
found on our website, www. imsb.ethz.ch. Questions regarding the position
should be directed to Dr Nicola Zamboni, email firstname.lastname@example.org (no
In line with our values, ETH Zurich encourages an inclusive culture. We
promote equality of opportunity, value diversity and nurture a working and
learning environment in which the rights and dignity of all our staff and
students are respected. Visit ourEqual Opportunities and Diversity website to
find out how we ensure a fair and open environment that allows everyone to
grow and flourish.
Apply online now