18 Oct 2023Job Information
Institute for Neurosciences of Montpellier, Inserm
Biological sciences » Biological engineering
Recognised Researcher (R2)
18 Dec 2023 - 17:00 (Europe/Paris)
Type of Contract
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
The Vision team of the INM is dedicated to the study of inherited retinal diseases (IRDs). The team is tightly linked to the National Reference Centre for Inherited Sensory Disorders and the Reference Medical Biology Laboratory for Neurosensorial Disorders of the Montpellier University Hospital. Our research is aimed at establishing genotype-phenotype correlations, resolving diagnostic impasses, elucidating pathophysiological processes and developing innovative therapies for IRDs. Using human disease-specific iPSC-derived retinal organoid models, the project aims to elucidate how different mutations within the same IRD gene can give rise to distinct retinal phenotypes and to the association of non-retinal symptoms (such as hearing loss). Moreover, using the same models, the project will evaluate the efficacy of CRISPR/Cas- mediated genome editing of specific mutations for phenotype reversal. Recent relevant publications from our team are PMID: 31909088; 36114559; 37654703; 37768732Requirements
PhD or equivalent
We are seeking a highly motived post-doctoral fellow with extensive and rigorous cell culture expertise. Experience in stem cell culture and differentiation would be an advantage. Molecular and cellular biology expertise is required. Strong writing, organisation, and communication skills are essential. Although autonomous, the applicant must be able to work collaboratively as part of a team.
International candidates are encouraged to apply. English oral and written skills are essential, French skills would be advantageous but not a prerequisite.
Years of Research Experience
Additional Information Work Location(s)
1 - 4
Number of offers available
Institute for Neurosciences of Montpellier, Inserm U1298
80 Avenue Augustin Fliche
GeofieldWhere to apply
https:// www. inmfrance.com
80 Ave Augustin Fliche