Umeå University, Faculty of Science and Technology
Umeå University is one of Sweden's largest institutions of higher
education with over 35,000 students and 4,200 faculty and staff. We are
characterised by world-leading research in several scientific fields and a
multitude of educations ranked highly in international comparison. Umeå
University is also the site of the pioneering discovery of the CRISPR-Cas9
genetic scissors - a revolution in genetic engineering that has been awarded
the Nobel Prize in Chemistry.
At Umeå University, everything is nearby. Our cohesive campus environment
makes it easy to meet, collaborate and exchange knowledge, which promotes a
dynamic and open culture where we rejoice in each other's successes.
Are you interested in knowing more about Umeå University as a workplace read
more at: Work with us.
The Department of Chemistry seeks a postdoctor for structure determination of
membrane-bound proteins of the Bcl-2 family involved in apoptosis. The
employment is full-time for two years with access January 1st, 2023 or by
agreement. Last day to apply is 14th October 2022.
Project description and working tasks
This postdoctoral position is part of a Swedish council financed research
project to unravel the regulation of programmed cell death at the molecular
level with focus on the structure of the proteins and biological membranes
involved in this important process. Important key players in the mitochondrial
(intrinsic) cell death pathway are membrane-active proteins of the Bcl-2
family. The main objective of this project is to understand the function - and
underlying structural properties - of these proteins and their interactions
with the mitochondrial membrane environment. For this purpose we will use
structural biological methods focusing on solid-state NMR spectroscopy of
lipid-protein complexes, complemented by liquid-state NMR. In addition, we
will also use neutron reflectometry on these lipid protein complexes). You
will primarily study the membrane bound Bcl-2 proteins and their mutual
interactions. In addition, you will also be supporting NMR based work on human
protein kinases which can be involved in human cancer, in part, through their
regulation of Bcl-2 proteins.
The Department of Chemistry offers access to an excellent research
infrastructure within the KBC environment (www. kbc.umu.se) with access to
solid phase/liquid 850 MHz NMR and neutron sources in Europe (mainly
ESS/ISIS). You will work with thriving small teams in a large
interdisciplinary environment with excellent infrastructure.
To be appointed under the postdoctoral agreement, the postdoctoral fellow is
required to have completed a doctoral degree or a foreign degree deemed
equivalent to a doctoral degree. This qualification requirements must be
fulfilled no later than at the time of the appointment decision.
To be appointed under the postdoctoral agreement, priority should be given to
candidates who completed their doctoral degree, according to what is
stipulated in the paragraph above, no later than three years prior. If there
are special reasons, candidates who completed their doctoral degree prior to
that may also be eligible. Special reasons include absence due to illness,
parental leave, appointments of trust in trade union organisations, military
service, or similar circumstances, as well as clinical practice or other forms
of appointment/assignment relevant to the subject area. Postdoctoral fellows
who are to teach or supervise must have taken relevant courses in teaching and
learning in higher education.
The doctoral degree should be within chemistry, biophysics, biochemistry or an
equivalent subject area.
Previous extensive experience of protein structure determination by solid-
state/liquid NMR is required. You shall have a keen interest in the area of
NMR-based structural biology and be prepared to take on scientific and
technological challenges. Good knowledge of English, both written and spoken,
and a very good ability to write scientific publications is required. You must
be creative with good teamwork skills, be initiative-driven and have a high
degree of independence.
Training and/or experience in biochemistry, structural biology and/or
biophysical chemistry, as well as neutron scattering on biological samples are
considered as strong merits. Previous experience with membrane proteins is
highly meriting. Insight in other structural biology methods and/or
biophysical approaches is of advantage.
A complete application should contain the following documents:
A cover letter including a description of your qualifications, research
interests and motivation for applying, and your contact information
(maximum 2 pages)
A curriculum vitae, including a publication list
Copies of your PhD thesis and relevant publications
Verified copies of degree certificates or equivalent alternatively
documentation providing information on when doctoral degree is expected to
be obtained, including documentation of completed academic courses and
Name and contact information of at least two reference persons
The application can be written in Swedish or English. Applications must be
submitted via our electronic recruiting system. Documents sent electronically
must be in Word or PDF format. The closing date is 14th October 2022.
For more information please contact Professor Gerhard Gröbner, phone:
+4690-7866346, email: firstname.lastname@example.org.
Information about the department
Department of Chemistry is the largest department in the Faculty of Science
and Technology, with approximately 200 employees, including about 40 doctoral
students, and with a strong and expanding research. Three major areas of
research; Biological Chemistry, Environmental and Biogeochemistry and
Technical Chemistry, represents the research and chemistry education of our
department. We are also a strong partner in KBC, The Chemical-Biological
Centre. For more information about working at Umeå University:
www. umu.se/en/work-with-us/. At Umeå University we have a vibrant postdoc
community that brings together postdoc across disciplines by arranging carrier
promoting activities (umeapostdocsociety.se).
Umeå University strives to offer an equal environment where open dialogue
between people with different backgrounds and perspectives lay the foundation
for learning, creativity and development. We welcome people with different
backgrounds and experiences to apply for the current employment.
We kindly decline offers of recruitment and advertising help.
Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment 2023-01-01, or by agreement
Number of positions 1
Working hours 100%
County Västerbottens län
Reference number AN 2.2.1-1275-22
Gerhard Gröbner, 090-7866346
Last application date 14.Oct.2022 11:59 PM CEST
Apply for position
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