Post-Doc

Universities and Institutes of Greece

Greece

October 10, 2022

Description

  • Organisation/Company: University of Crete
  • Research Field: Biological sciences › Biology
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 10/10/2022 23:00 - Europe/Athens
  • Location: Greece › Heraklion
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 40
  • Offer Starting Date: 01/11/2022
  • The mitotic spindle is a microtubule-based apparatus that is responsible

    for accurate segregation of the genetic material into two daughter

    cells during mitotic cell division. Defects in spindle formation can

    lead to aneuploidy, chromosomal instability or improper daughter

    cell-size, which are associated with tumorigenesis or developmental

    defects. However, the molecular mechanisms of spindle assembly are

    incompletely understood. In our lab, we have found novel proteins and

    novel phosphorylation sites on tubulin, which are essential for optimal

    density and efficient polymerization of spindle microtubules in human

    cells. Using state of the art methodologies such as replacement of

    endogenous proteins and in vitro reconstitution in combination with high

    resolution confocal microscopy, biochemistry analysis and live-cell

    imaging, we will further investigate the role of these novel proteins

    and phosphorylation sites we have discovered and their significance for

    cancer cell proliferation and survival.

    This job is for one post-doc, for 12 months, with a possibility for a

    renewal.

    Offer Requirements
  • REQUIRED EDUCATION LEVEL
  • Biological sciences: PhD or equivalent

    Skills/Qualifications

    BSc in Biology

    PhD in Molecular or Cell Biology or Biochemistry

    Specific Requirements

    Good knowledge of confocal microscopy and eukaryotic cell culture

    Contact Information
  • Organisation/Company: University of Crete
  • Department: Research Commitee (ELKE)
  • Organisation Type: Higher Education Institute
  • Website: https:// www. elke.uoc.gr
  • E-Mail: mastorak@uoc.gr
  • Country: Greece
  • City: Heraklion
  • State/Province: Crete
  • Postal Code: 70013
  • Street: University Campus, Voutes
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