Posting DetailsDepartment Lineberger Compr Cancer Center - 426801
Posting Open Date 05/11/2023 Application Deadline Open Until Filled Yes Position Type Postdoctoral Scholar Position Title Post-Doc Research Associate Vacancy ID PDS003852 Full-time/Part-time Full-Time Temporary Hours per week 40 FTE 1 Work Location Chapel Hill, NC Position Location Hiring Range Proposed Start Date Estimated Duration of Appointment 12 Months
Primary Purpose of Organizational Unit
The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service. OUR VISION Our vision is to be the nation's leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding. OUR MISSION Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond. Education: We will prepare tomorrow's health care professionals and biomedical researchers by facilitating learning within innovative curricula and team- oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce. Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.
The laboratory of Philip Spanheimer, MD at the University of North Carolina at Chapel Hill and the Lineberger Comprehensive Cancer Center is inviting applications for two funded positions to begin as early as April 2021. The Spanheimer lab studies mechanisms of transcriptional regulation associated with patterns of gene expression related to key phenotypic traits. Particular areas of emphasis are investigating how the program of estrogen response is maintained in estrogen receptor positive breast cancer and identifying novel therapeutic vulnerabilities in tumors that become unresponsive to antiestrogen treatment (Spanheimer et al. Clin Cancer Research 2014, Spanheimer et al. Ann Surg 2014, Spanheimer et al. Ann Surg Oncol 2015). We work with cell line and in vitro models, but as a surgeon we also have direct use of fresh human tumor specimens. We are developing novel experimental approaches with fresh cancer specimens using single cell sequencing. We use techniques such as chromatin immunoprecipitation sequencing, affinity purification mass spectroscopy, and genetic manipulations with siRNA to study effects of transcription factors on gene expression and transcription factor interactions. We work very closely and are physically next to the Chuck Perou lab.
Minimum Education and Experience Requirements
PhD or MD in Molecular Oncology, Genetics, or related field.
Required Qualifications, Competencies, and Experience
Preferred Qualifications, Competencies, and Experience
The ideal candidate will be highly motivated to join a vibrant research laboratory to take advantage of sophisticated model systems that we have developed. Candidates with prior experience in molecular biology, molecular genetics, cancer genomics, and/or computational biology will be preferred.
Special Physical/Mental Requirements Special Instructions
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Quick Link https: // unc.peopleadmin.com/postings/256734
Posting Contact InformationDepartment Contact Name and Title Rhiannon M. Groves
Department Contact Telephone or Email rhia[email protected] Postdoctoral Affairs Contact Information
If you experience any problems accessing the system or have questions about the application process, please contact the University's Equal Employment Opportunity office at (919) 966-3576 or send an email to [email protected].
Please note: The Equal Employment Opportunity office will not be able to provide specific updates regarding position or application status.
Equal Opportunity Employer Statement
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.Optional and Required Documents
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