We are looking for a young talented researcher for “omics” analyses of both
B. pertussis isolates and immune responses during severe pertussis in
infants, and their role on the occurrence of the fulminant form of pertussis,
through the investigations of the following aspects:
Bacterial transcriptomics profiling
Functional studies of virulence genes on cellular infection models
Microbial isogenic mutants and in vitro functional analyses
Immune cell phenotyping
Cytokines and chemokine secretion measurement
Transcriptomics profiling of immune cells
Theses analyses will serve as a prerequisite for the identification of new
candidate vaccine antigens to overcome the recent pathogen evolution and
considering specific immune responses in infants.
Skills. Strong experience in microbiology and experience in immunology.
Experience in transcriptomics will be appreciated. Experience in Bordetella
pathogenesis will be appreciated but is not absolutely required as it will be
provided by members of the lab. Innovative thinking, work autonomy and good
communication skills are important. English speaking and autonomous manuscript
writing skills are also necessary.
Environment. The candidate will work in the Brisse lab at Institut Pasteur
(https: // research.pasteur.fr/en/team/biodiversity-and-epidemiology-of-
bacterial-pathogens/), under the supervision of Dr. Julie Toubiana
(Associate Professor in Pediatric Infectious Diseases and Deputy Head of
Bordetella National Reference Center, PI of the project) and in collaboration
with the Center for Translational Science (https: // www. pasteur.fr/en/center-
Conditions. The monthly salary will correspond to the standards in France
and will depend on candidate experience. The contract will initially be for 12
months, and possibly extended for 1 or 2 years. The position is available as
early as November 2nd, 2022, although starting date can be delayed for a few
months if the chosen candidate has agenda constraints.
Application : Please send your application as a single pdf to Julie
Toubiana (firstname.lastname@example.org) with a detailed CV, a cover letter and
Postdoctoral Researcher in Intestinal Immune Responses
The Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3
Mucosal Immunology Group at the Kennedy Institute, to work within the Nuffield
lead to changes in the interactions between...
Research Associate (Fixed Term)
Applications are invited for a Research Associate position in malaria parasite
biology of Plasmodium parasites and, more specifically, the role of the
Pathology, University of Cambridge.
The candidate should have completed...
of Anaerobic Bacteria at Institut Pasteur, Department of Microbiology.
signals including differences in O2 tension and oxidative stress to
good model to decipher the impact of environmental pressures on the gut
colonization and infection processes...
Research Field: Biological sciences › Biology
Our team scientific activity is committed to basic and translational
functional genomic approaches to better characterize MNP diversity and their
acts in MNPs as an immune checkpoint during sterile...
laboratory at the Institut Pasteur in Paris.
In the laboratory we study how epigenetics contribute to establishing the
invasive infections begin, how asymptomatic colonizations are maintained, and
We have integrated histone modifications in phenotypic responses...
This is a key role in the Respiratory Virus and Microbiome Initiative
to contribute to a large-scale pathogen genomics programme led by Dr Ewan
Respiratory Virus and Microbiome Initiative (RVI) is a new initiative with...