Post-Doc In Synthesis Of Active Pharmaceutical Ingredients By Resonant Acoustic Mixing (Ram)

Universities and Institutes of France
December 22, 2022
Contact:N/A
Offerd Salary:Negotiation
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Contract Type:Temporary
Working Time:Full time
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  • Organisation/Company: Universite de Montpellier
  • Research Field: Pharmacological sciences › Pharmacy
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 22/12/2022 22:00 - Europe/Brussels
  • Location: France › montpellier
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 38
  • Offer Starting Date: 01/02/2023
  • Eu Research Framework Programme: HE
  • Reference Number: 2023-R0009
  • We are looking for a Post-Doc who wants to contribute to the allow successful delivery of APIs or key

    intermediates, by the use of novel technologies such Resonant Acoustic Mixing (RAM) as enabling

    mechanochemical technology. Mechanochemistry has been identified by IUPAC as one of the ten top

    emerging technologies that will change the world. A unique opportunity for you to work in a scientific area of

    great importance, innovative and disruptive, in a setting at the interface with the industrial needs and in close

    interactions with excellent academic groups members of the European Programme Horizon IMPACTIVE

    (Innovative Mechanochemical Processes to synthesize ACTIVE pharmaceutical ingredients).

    Main mission :

    Postdoc position will work under the responsibility of Dr. Evelina Colacino, who focuses on the development of

    sustainable methodologies for organic synthesis, with a special attention to the mechanochemical preparation

    of value-added compounds for the pharmaceutical industry, from laboratory to large-scale, by Resonant

    Acoustic Mixing (RAM).

    Activites :

    As a Post-Doc, you will deal with the synthesis and development of APIs or key intermediates, and their

    characterization (including at the solid state). Your main research objectives will be to propose and design

    straightforward access (meaning specifically route scouting) to APIs by mechanochemistry, in alternative to

    solution-based procedures and to improve the ecological footprint of each synthesis at laboratory and large

    scales. The daily synthesis work will be performed at the Université de Montpellier (Charles Gerhardt Institute

    of Montpellier, ICGM) in France.

    The research activity will mainly focus on:

    • Design of scalable and green routes for APIs or key intermediates by Resonant Acoustic Mixing (RAM) in

    batch, in alternative to solution-based processes currently used in the industry;

    • Investigation of the mechanochemical process parameters to be optimized depending on the reaction

    scale.

    • Green Chemistry metrics applied to the processes developed within the project ;

    • Solid state characterization of each APIs or key intermediates;

    • Process development to access new pharmaceutical forms.

    Contract for 12 months, with possibiliy to be extended for additional 24 months

    Eligibility criteria

    doctoral degree in a relevant field such as medicinal chemistry and preparative organic chemistry

    Selection process

    Send your CV and cover lettrer by email to : evelina.colacino@umontpellier.fr before 12/22/2022

    Offer Requirements Skills/Qualifications

    To qualify for the position of Post-Doc, you must have a doctoral degree in a relevant field such as medicinal

    chemistry and preparative organic chemistry. Experience in green chemistry, mechanochemistry and solid

    state characterization is considered meritorious for this position, but not compulsory.

    We are looking for you who can work independently but also in close collaboration with the group members

    and as a part of the European Programme Horizon IMPACTIVE. You can plan and organize your own work, take

    your own initiatives and responsibility, be analytical and creative and be able to deliver results in time. You

    also need to be able to report to the founders, hence, need good communication skills and an interest for

    multidisciplinary research.

    The position requires sound verbal and written communication skills in English

    Contact Information
  • Organisation/Company: Universite de Montpellier
  • Department: Human Resources
  • Organisation Type: Higher Education Institute
  • Website: https:// www. umontpellier.fr/
  • E-Mail: evelina.colacino@umontpellier.fr
  • Country: France
  • City: Montpellier
  • Postal Code: 34000
  • Street: 163 rue Auguste Broussonnet
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