We are looking for a Post-Doc who wants to contribute to the allow successful delivery of APIs or key
intermediates, by the use of novel technologies such Resonant Acoustic Mixing (RAM) as enabling
mechanochemical technology. Mechanochemistry has been identified by IUPAC as one of the ten top
emerging technologies that will change the world. A unique opportunity for you to work in a scientific area of
great importance, innovative and disruptive, in a setting at the interface with the industrial needs and in close
interactions with excellent academic groups members of the European Programme Horizon IMPACTIVE
(Innovative Mechanochemical Processes to synthesize ACTIVE pharmaceutical ingredients).
Main mission :
Postdoc position will work under the responsibility of Dr. Evelina Colacino, who focuses on the development of
sustainable methodologies for organic synthesis, with a special attention to the mechanochemical preparation
of value-added compounds for the pharmaceutical industry, from laboratory to large-scale, by Resonant
Acoustic Mixing (RAM).
As a Post-Doc, you will deal with the synthesis and development of APIs or key intermediates, and their
characterization (including at the solid state). Your main research objectives will be to propose and design
straightforward access (meaning specifically route scouting) to APIs by mechanochemistry, in alternative to
solution-based procedures and to improve the ecological footprint of each synthesis at laboratory and large
scales. The daily synthesis work will be performed at the Université de Montpellier (Charles Gerhardt Institute
of Montpellier, ICGM) in France.
The research activity will mainly focus on:
• Design of scalable and green routes for APIs or key intermediates by Resonant Acoustic Mixing (RAM) in
batch, in alternative to solution-based processes currently used in the industry;
• Investigation of the mechanochemical process parameters to be optimized depending on the reaction
• Green Chemistry metrics applied to the processes developed within the project ;
• Solid state characterization of each APIs or key intermediates;
• Process development to access new pharmaceutical forms.
Contract for 12 months, with possibiliy to be extended for additional 24 monthsEligibility criteria
doctoral degree in a relevant field such as medicinal chemistry and preparative organic chemistrySelection process
Send your CV and cover lettrer by email to : email@example.com before 12/22/2022Offer Requirements Skills/Qualifications
To qualify for the position of Post-Doc, you must have a doctoral degree in a relevant field such as medicinal
chemistry and preparative organic chemistry. Experience in green chemistry, mechanochemistry and solid
state characterization is considered meritorious for this position, but not compulsory.
We are looking for you who can work independently but also in close collaboration with the group members
and as a part of the European Programme Horizon IMPACTIVE. You can plan and organize your own work, take
your own initiatives and responsibility, be analytical and creative and be able to deliver results in time. You
also need to be able to report to the founders, hence, need good communication skills and an interest for
The position requires sound verbal and written communication skills in EnglishContact Information