Post-Doc Bioinformatician In Lymphoma Biology

Universities and Institutes of France

France

July 8, 2021

Description

  • Organisation/Company: CNRS – Inserm – Aix Marseille University
  • Research Field: Medical sciences › Medicine
  • Researcher Profile: Leading Researcher (R4) Established Researcher (R3)
  • Application Deadline: 08/07/2021 21:00 - Europe/Athens
  • Location: France › marseille
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: 40
  • Offer Starting Date: 01/07/2021
  • The post-doctoral fellow will join the team of Sandrine Roulland at the Centre d'Immunologie de Marseille -Luminy (Marseille, France). The team is interested in (epi)genetic deregulations associated with the development and progression of lymphoid malignancies in human and mouse models.

    The candidate will be in charge to analyze, integrate and interpret large- scale genomic data - with an emphasis on single-cell RNA sequencing data - to dissect and model the cellular heterogeneity of malignant B cells both in mice and mouse models and to determine the functional dynamics operating in these cells in relation to their immune microenvironment. Through cross-analyses, we also aim to decipher the biological mechanisms underlying relapse and resistance to therapy. The post-doctoral fellow will have to:

    - Ensure statistical and bioinformatics analysis of single-cell RNA-seq data generated by the team in lymphoma patients and animal models

    - Implement and develop new statistical methods and automated pipelines to analyze and visualize large sets of high throughput sequencing data

    - Analyze and interpret the results, communicate with collaborators and produce scientific publications.

    He/She will be hosted within a team of bioinformaticians with experience in the conception and development of single-cell data analysis pipelines.

    Offer Requirements Skills/Qualifications

    Required skills:

    - Advanced proficiency in R and PYTHON programming as well as tools ensuring reproducibility of analyses (Docker...) and version management (svn, git...).

    - Proficiency in the software required for the analysis of genomic data (STAR, picard, samtools, DEseq, EdgeR, Seurat, Monocle...).

    - Fluency in written and oral scientific English.

    - Practical understanding of mathematical methods for multidimensional data analysis (PCA, t-SNE, statistical learning, etc.) Experience with single- cell data would be a plus.

    - Knowledge of system administration under Unix/Linux, Shell.

    - Ensure scientific monitoring of analytical methods.

    - Dynamism, autonomy, initiative, organizational skills, and adaptability.

    Specific Requirements

    Profile of the candidate :

  • PhD in bioinformatics or computation biology in genomics.
  • Organizational skills. Strong ability to clearly present scientific results
  • Good communication with biology researchers and interest for biological questions.
  • Contact Information
  • Organisation/Company: CNRS – Inserm – Aix Marseille University
  • Department: Centre d'Immunologie de Marseille Luminy
  • Organisation Type: Research Laboratory
  • Website: https:// www. ciml.univ-mrs.fr/
  • E-Mail: denarnaud@ciml.univ-mrs.fr roulland@ciml.univ-mrs.fr
  • Country: France
  • City: Marseille
  • State/Province: France
  • Postal Code: 13009
  • Street: Parc Scientifique et Technologique de Luminy
  • Similar Jobs

    Add to favorites Read more...

    Post-Doctoral Position In The Group Of P.Milpied (Marseille, France) - Bioinformatics

    Location: France › Marseille cedex 09 the analysis of multimodal single-cell RNA-seq data from human lymphoma with expertise in the design and development of pipelines for single-cell data analysis strategies adapted to multimodal single-cell data....

    Add to favorites Read more...

    Bioinformatics Research Engineer

    Key words: Bioinformatics, transcriptomic, high-dimensional data, omics, Our laboratory is located in Lille (Northern France), a very active and Pasteur de Lille and the European Genomic Institute for Diabetes (EGID, development of metabolic diseases (https:...

    Add to favorites Read more...

    Analysis Of High-Throughput Sequencing Data And Generation Of Predictive Theoretical Models For...

    Research Field: Biological sciences › Biology Location: Italy › Roma Such networks will be studied through computational functional characterization of coding and non-coding RNA molecules, especially You can find the documentation required at: https: //...

    Katholieke Universiteit Leuven

    Belgium Jun 2, 2021

    Add to favorites Read more...

    Postdoctoral scientist: Bioinformatics for single-cell multi-omics research in human aging and Parkinson’s disease

    Postdoctoral scientist: Bioinformatics for single-cell multi-omics Center of Human Genetics, KU Leuven in the team of Prof. data analysis strategies for single-cell multi-omics data integration. Voet is a highly multidisciplinary team developing and using cutting-edge...