Planar Nanopore Bio-Electrofunctionalization Technology

Universities and Institutes of France

France

June 29, 2021

Description

  • Organisation/Company: Université Grenoble Alpes
  • Research Field: Engineering
  • Researcher Profile: First Stage Researcher (R1) Recognised Researcher (R2) Established Researcher (R3) Leading Researcher (R4)
  • Application Deadline: 29/06/2021 00:00 - Europe/Brussels
  • Location: France › Saint Martin d'Hères
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Offer Starting Date: 01/10/2021
  • Mission:

    Microfabrication of chips, electrofunctionalization by biomolecules, electrochemical characterization of deposits, electrochemiluminescence

    Main activities:

    List here the activities in the order of importance or quota

    During the first 3 months of his/her thesis, the student will be in charge of the microfabrication of nanochips at the CEA Upstream Technology Platform. Then, back to SyMMES/CREAB, he/she will be in charge of the synthesis of pyrrole-antibody and ruthenium-antibody conjugates according to existing protocols. He/she will use wire electrodes to set up electrofunctionalization and electrochemiluminescence and will benefit from the team's solid experience in electrochemistry (9 months). At the end of the first year, once the first biofunctionalization results are obtained, the fabrication of more elaborate devices with nanochannel alignments will be undertaken. Then, the functionalization of the nanochannels with antibodies will be undertaken and will result in a set of functionalized nanochannels at the end of the second year. These can be used to detect the passage of a protein by electrochemiluminescence. If successful, the first stimulation tests on a single cell, placed in a microreactor upstream of the nanochannels, will be undertaken during the last six months before the writing of the manuscript.

    Funding category: Contrat doctoral

    PHD title: Phd engineer sciences and instrumentation

    PHD Country: France

    Offer Requirements Specific Requirements
  • Trade skills/ expertise
  • The PhD student should have a background in nanotechnology. An internship experience in the field of biosensors is required. Letters of recommendation from previous supervisors and masters supervisors will be appreciated.

  • Personal skills
  • All candidates must be motivated, eclectic and easily integrated into a multi- disciplinary context.

    Experience in the public domain would be appreciated.

    Master in the field of nanotechnologies or biophysics

    Contact Information
  • Organisation/Company: Université Grenoble Alpes
  • Organisation Type: Public Research Institution
  • Country: France
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