Title: Characteristics of chiral molecules using chiroptical methods
supported by computational chemistry
Description: The main interest of our Laboratory for Spectroscopy,
Molecular Modeling and Structure Determination is characterizing chiral
molecules using molecular spectroscopy, X-ray diffraction and
computational methods. Chirality brings molecules a new dimension. For
example, enantiomers can differ in bioactivity, chiroptical spectra,
interactions with other chiral molecules, organoleptic properties. New
chiral materials can find use in asymmetric synthesis and catalysis, as
well as in chiral separation, chiral optoelectronics, chiral sensing, etc.
Recently, we have synthesized chiral naphthalenediimides based on which we
have constructed an enantioselective sensor for teratogenic (S)- and
therapeutic (R)-Thalidomide in blood plasma. Also, we studied new
chiroptic ECD-Raman spectra using some atropisomeric naphthalenediimides.
The PhD thesis can be devoted to some of the following topics:
experimental chiroptical spectroscopy,
computational chiroptical spectroscopy,
crystal structure determination
of a series of chiral substances such as chiral organic semiconductor
molecules or chiral lanthanide coordination complexes, etc.
PhD Position in Artificial Enzymes
The Department of Physics, Chemistry and Pharmacy, University of Southern
Denmark (SDU) in Odense invites applications for a PhD position in the field
in the field of enzyme catalysis, chemistry,...