Phd Student Position In Hrms-Based Exposomics At The French School Of Public Health (France) /...

Universities and Institutes of France

France

June 30, 2021

Description

  • Organisation/Company: Ecole des Hautes Etudes en Santé Publique EHESP
  • Research Field: Chemistry
  • Researcher Profile: First Stage Researcher (R1) Recognised Researcher (R2) Established Researcher (R3) Leading Researcher (R4)
  • Application Deadline: 30/06/2021 00:00 - Europe/Brussels
  • Location: France › Rennes
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Offer Starting Date: 01/11/2021
  • Chronic exposure of the general population to complex mixtures of chemicals is suspected of contributing to many adverse health outcome such as non- communicable chronic diseases (NCD) which are the major causes of premature death worldwide. Hence, deciphering the human chemical exposome (i.e. characterizing chemical mixtures and their transformation products accumulated in human biological matrices) and identifying the relevant chemical mixtures associated with NCDs would be a key step towards improving health and potentially reduce the overall burden of NCDs.

    To this aim, innovative holistic methodologies methods are acutely needed to make a step change in human exposure assessment and capture the high diversity of exposures human is facing daily. Importantly, many NCDs could have their origins in utero (developmental origins of health and disease – DOHaD); it is therefore essential to focus on one of the most critical and vulnerable periods of development, i.e. the prenatal period.

    The main objective of PhD will be to develop a robust standardized methodology to apply suspect screening and non-targeted analyses based on high-resolution mass spectrometry (HRMS) to profile placenta samples from mother-child cohort studies. Profiling placenta using untargeted methods offers many advantages to monitor fetal exposure as many xenobiotics have been shown to accumulate over time in the placenta.

    Funding category: Financement de l'Union européenne

    PHD Country: France

    Offer Requirements Specific Requirements

    We seek a highly motivated and enthusiastic candidate with a master degree in analytical chemistry and initial expertise in the area of HRMS-based exposomics, metabolomics, or analytical chemistry. Essential skills for this job include experience in biological sample preparation techniques; practical expertise in liquid chromatographic methods and/or gas chromatography.

    Contact Information
  • Organisation/Company: Ecole des Hautes Etudes en Santé Publique EHESP
  • Organisation Type: Public Research Institution
  • Country: France