PhD Student (f/m/d) with MSc in Biochemistry, Biology or Related Fields

Helmholtz Zentrum Berlin


February 15, 2022


PhD Student (f/m/d) with MSc in Biochemistry, Biology or Related Fields

Reference No.: PS 2022/3

The Macromolecular Crystallography (MX) group at the HZB is operating and developing three beamlines for MX at the BESSY II storage ring for the national and international user community. In addition, we are actively pursuing research projects in several areas of structural biology. A particular focus is laid upon high-throughput crystallography and compound screening. In the NECESSITY project, we will investigate a broad number of interesting compounds on the MX beamlines and identify those that could inhibit the main protease of SARS-CoV-2 together with researchers from the Med. University Innsbruck and Palacký University Olomouc. As a PhD student in our team, you will be significantly involved in our research.

Your tasks
  • You perform crystallographic fragment-screening.
  • You develop fragment-screening as a viable user experiment.
  • You utilise fragment-screening to develop compounds which inhibit the main protease of SARS-CoV-2.
  • You optimise initial hits to strong binders and inhibitors.
  • Your profile
  • MSc in Biochemistry, Biology, or related fields
  • Experience in molecular biology techniques
  • Experience in protein purification techniques
  • Expertise in carrying out fragment-screening experiments
  • Experience diffraction data collection and data handling
  • Your benefits at HZB
  • A job at one of the 18 Helmholtz centres,
  • Work in the research environment of the science metropolis Berlin,
  • Work-life balance through flexible working times, mobile working and consulting offices for work-life matters,
  • Health management and company sports programmes,
  • Financial support for public transport (Jobticket),
  • Continuing education opportunities,
  • 30 days paid leave,
  • A company pension scheme,
  • And a team that looks forward to working with you!
  • Fixed term contract for 36 months. The salary is based on the Collective Agreement for the German Public Service (TVöD-Bund).

    How to apply

    We look forward to receiving your application via our application management system by 15.02.2022. For reasons of data protection regulations, we are unfortunately unable to consider applications that reach us by email or by mail in the application process.

    We strive to increase the proportion of female employees and are therefore particularly pleased to receive applications from women. Disabled applicants with equal aptitude are given preference.

    For German version, please click on the following link: German Version.