PhD Scholarship – Genetic and epigenetic markers of prostate cancer aggressiveness

Monash University
December 31, 2023
Offerd Salary:$33,000
Working address:N/A
Contract Type:Other
Working Time:Full time
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PhD Scholarship – Genetic and epigenetic markers of prostate cancer


Job No.: 657579

Location: Monash Medical Centre (Precision Medicine, School of Clinical Sciences at Monash Health, Monash University)

Employment Type: Full-time

Duration: 3-year fixed-term appointment

Remuneration: The successful applicant will receive a tax-free stipend, at the current value of $33,000 per annum 2023 full-time rate, as per the Monash Research Training Program (RTP) Stipend www. scholarships/scholarships/find-a-scholarship/research-training-program- scholarship#scholarship-details.

  • Amplify your impact at a world top 50 University
  • Join our inclusive, collaborative community
  • Be surrounded by extraordinary ideas - and the people who pursue them
  • The Opportunity

    Precision medicine seeks to enhance health and wellbeing by tailoring medical interventions to individuals who are most likely to benefit from them, with a focus on recognising individual diversity. Our vision is to provide equitable access to precision medicine through extensive, globally connected, interdisciplinary population-based epidemiological and clinical studies of human diseases. These studies inform clinical trials and population-based screening initiatives. Monash University's top-tier infrastructure facilitates the growth of our precision medicine program, offering numerous opportunities for professionals, academics, and postgraduate students who share our commitment to delivering evidence-based precision medicine to our community.

    Prostate cancer is the most commonly diagnosed cancer in Australian men. Overall survival is high but distinguishing the aggressive disease from indolent tumours is a challenge. This PhD project will involve using genome- wide genetic and epigenetic data to better characterise prostate cancer aggressiveness. The germline and tumour genomic data that have been collected currently include whole-exome sequencing, single nucleotide polymorphism array, targeted panel for high-risk predisposition genes (e.g., BRCA1/2 , ATM , CHEK2 ) and genome-wide DNA methylation. Extensive clinical and sociodemographic information are also available in our resource.

    We seek a talented and highly motivated person with a strong quantitative background in genetic epidemiology, statistical genetics, bioinformatics, or biostatistics. The candidate will be expected to use a range of statistical and bioinformatics methods to derive (multi-omic) molecular signatures of prostate cancer aggressiveness and investigate their clinical usefulness.

    Eligibility requirements:

    Candidates will need to fulfil the Monash University minimum requirements for admission to a PhD detailed here: www. requirements/minimum

    How to Apply

    For general instructions on how to apply for roles at Monash, please refer to "How to apply for Monash Jobs".

    To express your interest in this scholarship and PhD research opportunity, we request candidates provide:

  • A cover letter describing your research interests and why you would like to undertake a PhD (maximum one page)
  • A CV including qualifications, academic achievements, list of publications, work history and references
  • A copy of your academic transcript(s)
  • Enquiries

    Pierre-Antoine Dugué, Senior Research Fellow, [email protected]

    Melissa Southey, Professor, [email protected]

    Closing date

    Sunday 31 December 2023, 11:55pm AEDT

    Please note: Monash University will be closed from Thursday 21 December 2023 until Monday 1 January 2024 inclusive.

    At Monash University, the health, safety and wellbeing of our staff, students and visitors is our top priority. In accordance with the Pandemic Orders issued by the Victorian Government Health Minister, we require all staff working or placed in healthcare facilities to be fully vaccinated (boosted) against COVID-19 or have an approved medical exemption from receiving a COVID-19 vaccine in order to attend these locations.

    For the latest information on COVID-19 at Monash, please visit our website.

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    Monash University recognises that its Australian campuses are located on the unceded lands of the people of the Kulin nations, and pays its respects to their elders, past and present.

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