PhD Project: Computational study of biofabrication for artificial tissue generationUniversität Bayreuth • Theoretische Physik • Bayreuth

Germany Universities

Germany

August 31, 2021

Description

Open Positions 1

Time Span 01 Nov 2021 for 4 years Application Deadline 31 Aug 2021 Financing yes Type of Position

  • PhD - Doctoral Programme
  • Field of Research

  • Mathematics / Natural Sciences
  • Engineering
  • Subjects Theoretical Physics Description Biofabrication, the 3D printing of living cells, is a fascinating new approach to produce living artificial tissue and to overcome the shortage of donor organs in hospitals. Currently, however, the widespread use of this technology is prevented by a number of problems. The most severe of these is the high percentage of cells being killed or damaged by mechanical stresses during printing. The SFB/TRR 225 at the Universities of Würzburg, Erlangen and Bayreuth addresses this problem in a joint effort by around 20 research groups from chemistry, biology, medicine and physics.

    The current project is part of this effort and aims to develop a computational scheme which allows efficient and accurate computer simulations of biofabrication. Using this novel tool and in collaboration with our experimental colleagues we will thrive to understand the physical origin of mechanical cell damage and its biological consequences. Based on these insights we will finally develop new techniques to enable the biofabrication of living cells with nearly 100% survival rate.

    Simulations will be run using the ESPResSo simulation package which will need to be extended by the prospective candidate. Analysis tools will be written by the candidate in C/C++. The required supercomputer ressources will be provided by the local computing cluster available at the University of Bayreuth as well as by projects on national supercomputing systems such as SuperMUC and JURECA.

    The successful candidate must possess a strong background in theoretical physics, numerical mathematics, computational engineering or a similar discipline. Interest in writing and using computer codes (C/C++) is required. A background in fluid mechanics or biology is desirable, but not explicitly required. Research will be conducted in the Biofluid Simulation and Modelling group at the University of Bayreuth, Germany. Bayreuth is a medium- sized town with a large student population and is situated in a beautiful natural setting between the mountains of the "Fränkische Schweiz" and "Fichtelgebirge".

    For applications or further information please contact: Stephan Gekle, stephan.gekle@unibayreuth.de, or see our website biofluid.physik.uni- bayreuth.de

    Working Language

  • English
  • German
  • Language of Dissertation

  • English
  • Required Documents

  • CV
  • Reports, certificates
  • Transcripts
  • Letter of Motivation
  • More Information https: // www. gekle.physik.uni- bayreuth.de/en/jobs/Biofabrication.pdf

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