Umeå University, Faculty of Medicine
Umeå University is one of Sweden's largest institutions of higher
education with over 35,000 students and 4,200 faculty and staff. We are
characterised by world-leading research in several scientific fields and a
multitude of educations ranked highly in international comparison. Umeå
University is also the site of the pioneering discovery of the CRISPR-Cas9
genetic scissors - a revolution in genetic engineering that has been awarded
the Nobel Prize in Chemistry.
At Umeå University, everything is nearby. Our cohesive campus environment
makes it easy to meet, collaborate and exchange knowledge, which promotes a
dynamic and open culture where we rejoice in each other's successes.
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The Faculty of Medicine, which consists of 13 departments, is responsible for
biomedical research and courses in the field of nursing and health care and
has an extensive research and graduate education in more than 80 subjects.
The Department of Integrative Medical Biology is now announcing a Ph.D student
position. The position is on fulltime for four years, starting 1st of December
2022 or upon agreement.
Description of the PhD-Project
Cannabinoid CB1 and dopamine D2 receptors can physically interact to form
CB1/D2 heteromers that could constitute important therapeutic targets for a
wide range of CNS disorders. However, the pharmacological importance of this
interaction is yet to be determined on a molecular level. The main hypothesis
we are addressing is that bidirectional allosteric interactions within CB1/D2
heteromers have functional consequences for the activity of receptor complexes
in both the healthy and diseased brain. Hence, the main goal of this project
is to use pharmacology to characterize the effects of different CB receptor
ligands on CB1/D2 heteromer-specific signalling. The project will take
advantage of the key strengths of different model systems - from transfected
human cell lines, mouse/human stem cell-derived neuronal models, to a
pharmacological model of schizophrenia in vivo using zebrafish.
The applicant is required to have completed a university level degree of at
least 240 ECTS credits, of which at least 60 ECTS credits are at Master
Specific admission requirements
In order to be admitted to postgraduate studies, it is required that the
necessary knowledge from university higher education or corresponding
education and/or special professional experience that is assessed in
relation to the research area.
good skills in both spoken and written English are a requirement for the
position. Evaluation of these skills is made by having the intended PhD
student present his/her research plan in English for the Department's
designated postgraduate education group.
In addition, the applicant should, through university studies or other
equivalent education, have gained basic theoretical knowledge in pharmacology
or biomedicine and have experience of laboratory work and method development.
Practical experience of cell culturing and experience of different biochemical
methods of analysis is considered a very strong merit. The applicant should be
able to work both independently and as part of a team, and high focus will be
given to the candidate's potential collaborative skills.
Terms of employment
The appointment aims at a PhD degree and the main task of the PhD student is
to pursue doctoral studies, which includes participation in research, seminars
and courses. According to the Swedish Higher Education Ordinance (Chapter 12,
Section 2), the decision on employment as a PhD student cannot be appealed.
The employment is limited to four years full-time starting 2022-12-01 or upon
agreement. The salary corresponds to the established salary level for doctoral
The application shall be written in English or Swedish, documents must be in
Word or pdf format. Applications must be submitted electronically using the
e-recruitment system of Umeå University Varbi and be received no later than
2022-10-16 . A complete application should contain the following
A cover letter including a description of your research interests, your
reasons to apply for the position, and your contact information
A curriculum vitae
Certified copies of degree certificates and other completed academic
Contact information for two reference persons
Other and contact
For more information please contact Professor Stig Jacobsson,
You who are admitted to doctoral studies at the Faculty of Medicine will be
enrolled in the faculty-wide doctoral education programme. The doctoral
programme comprises 25 credits and is offered in two study variants: 25
credits spread over 8 terms (a total of 4 years) or over 12 terms (a total
of 6 years), starting each autumn and spring semester. More information about
the programme can be found on the faculty's web page for doctoral studies
(https: // www. aurora.umu.se/en/organisation-and-
Welcome to apply!
Umeå University strives to offer an equal environment where open dialogue
between people with different backgrounds and perspectives lay the foundation
for learning, creativity and development. We welcome people with different
backgrounds and experiences to apply for the current employment.
We kindly decline offers of recruitment and advertising help.
Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment 2022-12-01 or upon agreement
Salary monthly salary
Number of positions 1
Working hours 100%
County Västerbottens län
Reference number AN 2.2.1-1396-22
Stig Jacobsson, firstname.lastname@example.org
Last application date 16.Oct.2022 11:59 PM CEST
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