PhD position in Bioinformatics

PhD position in Bioinformatics PhD position in Bioinformatics

The Institute of Molecular Medicine (IMM) at SDU

PhD position in Bioinformatics

Institute of Molecular Medicine (IMM) aims to generate new knowledge on the function of the human body and disease mechanisms, thereby contributing to improved human health. IMM hosts an interdisciplinary group of experts in neurobiology and cancer biology and is in close proximity to the experts in genomics, proteomics and chromatin biology. Such a promising environment elicits translational collaborations with clinical practice and research toward understanding mechanisms underlying the pathophysiology of various human diseases.

Applications are invited for a PhD position in Bioinformatics in the laboratory of DNRF Chair and Novo Nordisk Faculty Prof. Vijay Tiwari (https: // www. tiwarilab.com/). Tiwari lab works on single-cell genomics and gene regulation, combining new single-cell and spatial omics technologies with bioinformatics and machine learning. In this project, the student will employ computational strategies to identify human genetic variation linked to cell fate changes in neurodevelopmental disorders and cancer. The candidate can use and combine single-cell ATAC-seq, single-cell RNA-seq, spatial gene expression, and whole-genome sequencing (with long reads) data. The candidate will get the opportunity to explore new analysis methods using deep learning. Depending on the interest, it is also possible to be involved in the wet lab, to perform single-cell sequencing and other experiments.

To learn more, please refer to the selected publications from the Tiwari lab:

Nature Cell Biology , 2022, 24, 1265–1277; Genes & Development, 2020, Sep; 34(17-18):1190-1209; Nature, 2019, Mar; 567(7746):113-117; Cell Stem Cell , 2018, Oct 4; 23(4):557; Nature Communications, 2017 Nov 15;8(1):1523; The EMBO Journal , 2016 Jan 4;35(1):24-45; J Cell Science , 2015 Dec 1;128(23):4380-94; The EMBO Journal , 2015 Aug 13;34(16):2162-81; Genome Research , 2015 Sep;25(9):1309-24; Nature Communications , 2013, Sep 27; 4:2478; Cancer Cell , 2013, 23, 768-783; PNAS , 2012 Apr 17;109(16): E934-43; Nature Genetics , 2012 Jan; 18;44(1):94-100; Nature , 2011 Dec 14;480(7378):490-5.

You will

Employ new computational strategies to identify human genetic variation linked to cell-fate changes in neurodevelopmental disorders and cancer.

Analyze bulk, single-cell and multi-omics datasets

Lead projects on gene regulatory mechanisms that contribute to the development and disease

Maintain accurate and detailed records of research activities

Gain training in internationally competitive and multidisciplinary Data Science research

Required Qualifications

MSc in Bioinformatics, Computer Science, Physics, Engineering, Bio- engineering, or equivalent.

Experience in Programming (R and/or Python).

Strong analytical, organizational, and record-keeping skills

Interest in working in a multidisciplinary and multicultural team

Willing to collaborate with internal and external collaborators

We offer

The possibility to engage in high-impact, multidisciplinary research

A stimulating, diverse and international research environment

Full funding for three years

Advanced training opportunities

Highly motivated research team and international collaborations

Access to state-of-the-art equipment and facilities

A supportive scientific and social network, including mentoring and career development

A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.)

Support with practical, social, and legal aspects (e.g. housing, visa, tax etc.) through our international staff office (ISO) and the Institute

Application should include

A letter stating your specific interest, motivation, and qualifications for the Tiwari laboratory and project (max. two pages).

A detailed CV, including personal contact information (max three pages).

Master's degree.

Contact details of two referees.

Applications must be submitted electronically using the link "Apply online" latest on February 15 th, 2023.

Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply. In the field "Projektbeskrivelse" please uploade an empty document.

Only applications submitted online and written in English will be accepted for evaluation. Applications may be shortlisted. Incomplete applications and applications received after the deadline will neither be considered nor evaluated.

The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations).

For further information, please contact Professor Vijay Tiwari at [email protected]

Living and Working in Denmark

Foreign applicants will be offered Danish language training as part of the employment. The International Staff Office (ISO) at SDU provides a variety of services for new employees, guests and people who consider applying for a job at the University of Southern Denmark. Among other things, the staff answers questions concerning salary, taxation, housing and accompanying family.

Further information for international applicants about entering and working in Denmark.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Deadline for Applications: 15th Feb 2023.

Start date: 1st April 2023 or later.

Campus: Odense

Application deadline: 15/02/2023