Description

Faculty of Health and Medical Sciences University of Copenhagen

We are looking for a highly motivated PhD student to join our team in field of mitochondrial dysfunction and its role in controlling neurodegeneration and behaivor research to commence autumn 2022.

Our research Our team is interested to understand molecular pathways by which mitochondrial dysfunction contribute to neurodegeneration and behaivor outcome in particular during inflammatory processes of central nervous system like in Parkinson's disease.

Your job You will join a multi-disciplinary research team but you will work independently with capacity and previous documented master thesis experience in related field. Your tasks will include; performing behaivoral studies and experiments in vivo models of neurodegeneration and inflammatory diseases. Previous work during bachelor and/or master thesis with mitochondrial biology and behaivoral sciences. The candidate is required to have documented experience with cellular and molecular immunology techniques such as Western blotting qPCR etc. You should be able to establish/utilize multiple techniques to assess mitochondrial functions such as seahorse technique, oxidative stress, mitochondrial DNA damage responses composed of molecular biology, biochemical techniques, Western blotting, immunohistochemistry and imaging techniques (including confocal).

Profile We are looking for a highly motivated and enthusiastic candidate with interest or track-record in the following competencies and experience:

Essential experience and skills

You have a MSc. in neurodegeneration / neuroimmunology not older than two years

You have documented experience in technologies related to mitophagy, mitochondrial functions and mitochondrial DNA biology

You have FELASA licence and experience working with rodents, autoimmune/brain inflammatory models and/or behaivor

Good English skills, written and spoken

Desirable experience and skills

Experience and knowledge in analysis of tissue inflammatory/autoimmune and neurodegenerative disease models, in vivo rodent models, histopathology, mitochondrial homeostasis and mitophagy, microscopy and imaging, imaging analysis (FIJI, Slidebook, Amira) and protein biochemistry

Place of employment The place of employment is at BRIC, Biocenter, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and the state-of-the-art technologies.

Terms of salary and employment The employment as PhD Fellow is a full time (37 working hours) and fixed- term position for 3 years. Starting date is October 1st, 2022. The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. Currently, the monthly salary starts at 28,365.85 DKK / approx. 3.813 Euro (April 2022-level). The employer will pay an additional 17.1 % to your pension fund.

Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The position is covered by the 'Memorandum on Job Structure for Academic Staff at the Universities of December 11, 2019 '.

Questions For further information regarding the position, please contact shohreh.issazadeh@bric.ku.dk

Application Your application should in English include:

Letter of application addressing the requirements (max. one page)

Curriculum Vitae

Two letters of support from current and/or previous supervisors

Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other languages than English or Danish

If you have not completed your master's degree a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.

As a prerequisite for a PhD fellowship employment, your master's degree must be equivalent to a Danish master's degree. For more information on whether your master's degree is equivalent to a Danish master's degree please read here. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science.

Please submit your application by clicking on "Apply Now" below. Only online applications will be accepted.

Application deadline: 2 July 2022, 23:59 CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates.