Heart development and regeneration in the zebrafish
The group of Nadia Mercader is interested in understanding the mechanisms of
heart development and regeneration. For this, they combine in vivo imaging,
genetics and omics approaches using the zebrafish model organism.
Downregulation of WT1 transcription factor gene expression is required to
promote myocardial fate. Biorxiv. doi: 10.1101/2021.07.06.451274
Adult sox10+ Cardiomyocytes Contribute to Myocardial Regeneration in the
Zebrafish. Cell Rep. doi: 10.1016/j.celrep.2019.09.041
Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is
Required for Organ Regeneration in the Zebrafish. Cell Rep. doi:
Model systems for regeneration: zebrafish. Development. doi:
Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial
cells. Development. doi: 10.1242/dev.174961
Transient fibrosis resolves via fibroblast inactivation in the regenerating
zebrafish heart. Proc Natl Acad Sci U S A. doi: 10.1073/pnas.1716713115
MSc Degree in Life Sciences or Biomedical Sciences
Fluent in English, knowledge in German will be a plus
Experience in use of the zebrafish model organisms, genome editing, or
Fluorescent Light Microscopy imaging and image analysis
High motivation and team-spirit
A PhD Position for 3 + 1 years.
A stimulating, cooperative, and supportive environment and close
collaboration with international research teams.
Dedicated PhD Specialisation Programs in Cutting Edge Microscopy and Stem
Cells and Regenerative Medicine.
The University of Bern is an equal opportunity employer and welcomes all
individuals who will contribute to the diversity and excellence of the
The group is located at the Institute of Anatomy, within the Medical
faculty of the University of Bern. It is also embedded into the Bern
Center for Precision Medicine, Department of Biomedical Research and
Cardiovascular research Cluster Bern that includes several groups working
at the University of Bern and University Hospital Inselspital.
Starting date: April 2022 or upon agreement
Please send a curriculum vitae, copy of academic record, statement of
experience, letter of motivation and contact information of 2 references to
email@example.com (email subject PhD position Mercader group 2022).