We are offering a PhD fellowship in Metabolic receptology and cancer
commencing October 1, 2021, of after agreement.
Our group and research:
The Novo Nordisk Foundation Center for Basic Metabolic Research's vision is to
strengthen interdisciplinary research that transforms our basic understanding
of the mechanisms that underlie metabolic health and disease, and to
accelerate this knowledge toward new prevention and treatment strategies. We
were established in 2010 and in 2017, we moved into new laboratories, offices
and meeting rooms in the Maersk Tower www. maersktower.ku.dk.
The Center has around 260 employees who work in an international, highly
collaborative research environment across a range of biomedical disciplines.
You can read more about us here: www. cbmr.ku.dk.
The aim of the Schwartz Group is to characterize and understand how signaling
metabolites and their specific GPCR sensors interact with hormonal and
neuronal mechanism to control endocrine and metabolic functions as the basis
for developing novel means to prevent and treat obesity and diabetes.
More information about the group can be found here.
We are seeking an enthusiastic, passionate PhD fellow to investigate SUCNR1
activation in development, progression and metastasis of cancer and further
investigate the receptors effect in different subsets of human immune cells.
The PhD fellow will focus on experimental and analytical strategies within in
vivo experiments, single cell transcriptomics and analysis of human tumors to
outline the role of SUCNR1 in immune responses and cancer. The applicant will
work with both human and animal tissue samples as well as perform cell-based
work, learning and applying a variety of techniques. The position provides an
opportunity to develop expertise in different cancer models, single cell
transcriptomics and an array of in vitro based experiments to completely
characterize SUCNR1 signaling pathways.
Principal supervisor is Professor Thue W. Schwartz, Novo Nordisk
Foundation Center for Basic Metabolic Research, E-mail: email@example.com
Start: October 1, 2021 or after agreement
Duration: 3 years as a PhD student
Your key tasks as a PhD student at SUND are:
Carry through an independent research project under supervision
Complete PhD courses or other equivalent education corresponding to
approx. 30 ECTS points
Participate in active research environments including a stay at another
Write a PhD thesis on the grounds of your project
Investigate immune cell infiltration and cancer metastasis of different
SUCNR1 expressing tumor cells in a syngeneic mouse model.
Analyze primary tumors with single cell transcriptomics.
Make molecular interpretation of data and communicate the results both
nationally and internationally
Will be working both individually and together with collaborators across
multiple scientific fields focused on improving our molecular
understanding of immune cells and cancer.
Key criteria for the assessment of applicants
Must have a master degree in Molecular Biomedicine, Biochemistry or
Expertise within GPCRs is a must and extensive experience with immune
cells and cancer is preferable
Professional qualifications relevant to the PhD programme including hands-
on experience with an array of in vitro based signaling assays including
IP signaling, cAMP signaling, arrestin recruitment, western blotting,
transcription factor, RT-qPCR, protein-protein interaction assays, etc.
Practical skills in cell culture and expression assays
Hands-on experience with single cell transcriptomics
Experience with software for large data sets (R)
FELASA ABD Certificate for in vivo mouse work
Ability and enthusiasm to learn new methods and techniques
Good communication skills in English, both oral and written (Danish is
Highly ambitious and self-driven
Strong work ethics and team player mentality
Previously demonstrated a capacity for excellence, either during master's
degree or publications
The preferred applicant will possess an excellent academic track record and be
highly motivated to perform science to extract novel findings of importance to
SUCNR1 activation in immune responses and cancer development, progression and
metastasis. We are particularly interested in candidates already familiar with
the metabolism field, especially nutrient sensing and metabolic receptology.
Place of employment
The place of employment is at the Novo Nordisk Foundation Center for Basic
Metabolic Research, Faculty of Health and Medical Sciences, University of
Copenhagen. We offer creative and stimulating working conditions in dynamic
and international research environment. Our research facilities include modern
laboratories, bioinformatics and statistic guidance, and access to big data
from multiple cohorts.
Terms of employment
The employment as PhD fellow is full time and for 3 years. The starting date
is October 1, 2021, or after agreement.
It is conditioned upon the applicant's successful enrolment as a PhD student
at the Graduate School at the Faculty of Health and Medical Sciences,
University of Copenhagen. This requires submission and acceptance of an
application for the specific project formulated by the applicant
The PhD study must be completed in accordance with The Ministerial Order on
the PhD programme (2013) and the Faculty's rules on achieving the degree.
Salary, pension and terms of employment are in accordance with the agreement
between the Ministry of Finance and The Danish Confederation of Professional
Associations on Academics in the State. Depending on seniority, the monthly
salary begins around 26.755 DKK /approx. 3.567 EUR (April 2018-level) plus
For specific information about the PhD fellowship, please contact the
General information about PhD study at the Faculty of Health and Medical
Sciences is available at the Graduate School's website:
https: // healthsciences.ku.dk/phd/guidelines/
Your application must be submitted electronically by clicking ‘Apply now'
below. The application must include the following documents in PDF format:
1. Motivated letter of application (max. one page)
2. CV incl. education, experience, language skills and other skills relevant
for the position
3. Master of Science diploma and transcript of records. If not completed, a
certified/signed copy of a recent transcript of records or a written statement
from the institution or supervisor will do
4. Publication list (if possible)
Application deadline: 22 June 2021, 23.59pm CET
We reserve the right not to consider material received after the deadline, and
not to consider applications that do not live up to the abovementioned
The further process
After the expiry of the deadline for applications, the authorized recruitment
manager selects applicants for assessment on the advice of the hiring
committee. All applicants are then immediately notified whether their
application has been passed for assessment by an unbiased assessor.
The assessor makes a non-prioritized assessment of the academic qualifications
and experience with respect to the above-mentioned area of research,
techniques, skills and other requirements listed in the advertisement.
Once the assessment work has been completed each applicant has the opportunity
to comment on the part of the assessment that relates to the applicant
You can read about the recruitment process at
https: // employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of
13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wishes to reflect the diversity of society and
welcome applications from all qualified candidates regardless of personal