Phd Candidate (Pre Doc, Research Assistant, 30 Hrs) (F/M/D) Pharmacology

Universities and Institutes of Austria

Austria

December 23, 2021

Description

  • Organisation/Company: Karl Landsteiner Privatuniversität
  • Research Field: Pharmacological sciences › Clinical pharmacology
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 23/12/2021 22:00 - Europe/Athens
  • Location: Austria › Krems
  • Type Of Contract: To be defined
  • Job Status: Part-time
  • Hours Per Week: 30
  • Is The Job Related To Staff Position Within A Research Infrastructure?: Yes
  • Established in 2013, the Karl Landsteiner University of Health Sciences (KL) is part of an academic and research community located at the Campus Krems and includes a network of comprising teaching hospitals in St. Pölten, Krems and Tulln. The university offers degree programmes in Human Medicine, Psychotherapy, Counselling Sciences and Psychology, which are tailored to the requirements of the Bologna model, opening the door to new, cutting-edge health professions. KL is committed to raising its profile in specific areas of biomedicine, biomedical engineering, and biopsychosocial sciences by entering into strategic academic and research partnerships with other institutions. With immediate effect, the KL offers a 3-year research position at the Division “Pharmacology” (Head: Univ. Prof. Dr. Dagmar Stoiber- Sakaguchi):

    PhD Candidate (Pre Doc, Research Assistant, 30 hrs) (f/m/d)

    Offer Requirements Skills/Qualifications

    Your tasks:

    • Participation in the research projects at the Division Pharmacology (PhD thesis)

    • Development and conducting of in vivo and in vitro (cell culture) models using molecular biology, immunological and immunocytological methods

    • Supervision of students and participation in teaching

    Information on the research project: Myeloproliferative neoplasms (MPNs) are a group of hematologic diseases dependent on activation of the Janus Kinase (JAK) –Signal Transducer and Activator of Transcription (STAT) pathway. Ruxolitinib, a JAK1/JAK2 inhibitor, is an efficient treatment approach in MPNs but leads to a severe impairment of innate immunity, especially natural killer (NK) cells. Using a mouse model of mutant CALR-driven MPN, in vitro human systems and patient samples, we plan to investigate the effects of mutant CALR on NK cell development and function at different disease stages. Further, we aim to compare the effect of novel JAK2- specific inhibitors on the disease progression and on NK cells with Ruxolitinib. Methods: Molecular biology, cell culture, flow cytometry, histology

    Specific Requirements

    Your profile:

    • Diploma or master's degree in life sciences

    • Interest in science and in conducting a PhD thesis project

    • Preferred: Background in molecular biology, cell biology, immunology and/or mouse models

    • Previous experience with mouse models and/or immunological methods will be considered as advantage

    • Willingness to participate in teaching and mentoring students

    • Ability to plan and pursue experiments independently

    • Mobility (collaboration project with University of Veterinary Medicine, Vienna)

    • Friendly, open appearance and team spirit

    Your Perspective:

    You can expect a challenging job in a highly motivated team. KL is committed to an anti-discriminatory employment policy and values equal opportunities and diversity. KL specifically encourages qualified people with different diversity characteristics (gender, age, ethnicity, denomination, sexual orientation, etc.) to apply. The minimum monthly gross salary for this position is 2,200 (30 hrs) gross per month.

    Applications should include a motivation letter, curriculum vitae and credentials and should be mailed by 31st of December 2021 referring to jobnumber “2137” to Ms. Christina Schwaiger of the Karl Landsteiner University of Health Sciences, Dr.-Karl-Dorrek-Straße 30, 3500 Krems, Austria (bewerbung@kl.ac.at).

    Contact Information
  • Organisation/Company: Karl Landsteiner Privatuniversität
  • Organisation Type: Higher Education Institute
  • Website: https:// www. kl.ac.at
  • E-Mail: bewerbung@kl.ac.at
  • Country: Austria
  • City: Krems/Donau
  • Postal Code: 3500
  • Street: Dr.-Karl-Dorrekstrasse 30
  • Similar Jobs

    Add to favorites Read more...

    H2020-Msca Cofund Phd Position In Molecular Mechanisms Of Diseases

    Research Field: Biological sciences › Laboratory animal science The University of Padua and the Laboratory of Angiogenesis and Cancer of Biology, University of Padua, lead by Prof. Santoro are seeking PhD candidates for a Horizon...

    Add to favorites Read more...

    Postdoctoral Fellow (M/F) In Transplant Immunology And Immunotherapy, Nice, France

    Research Field: Biological sciences Medical sciences Pharmacological Location: France › NICE The TNT team, Innovative molecular and cellular Therapies in Nephrology and preclinical development of new immunotherapy approaches to prevent allograft candidate will develop and...

    Maastricht University

    Netherlands 4 days ago

    Add to favorites Read more...

    PhD candidate on development of immunotherapy for cancer, Faculty of Health, Medicine and Life Sciences, School GROW - Department of Internal Medicine

    We have demonstrated clinical efficacy of NK cells, both in models for of NK cells in metastatic (lobular) breast cancer, bringing groups together to combine knowledge on NK cells and preclinical breast cancer models. anti-tumor...

    Germany Universities

    Germany Nov 19, 2021

    Add to favorites Read more...

    PhD project: Engineered commensal lactobacilli as living therapeutic materials for chemoprevention of chronic inflammation and infection-associated carcinogenesis in the female genital tract at Leibniz-Science Campus Living Therapeutic MaterialsSaarland University Medical Center • Institute of Virology • Homburg

    Subjects Virology/Drug delivery Description PhD position available at the Institute of Virology, Saarland University Medical Center, Homburg/Saar, Germany, in collaboration with the Leibniz Institute for New Project: Engineered commensal lactobacilli as living therapeutic materials for...

    Maastricht University

    Netherlands 4 days ago

    Add to favorites Read more...

    Technician on development of immunotherapy for cancer, Faculty of Health, Medicine and Life Sciences, School GROW - Department of Internal Medicine

    We have demonstrated clinical efficacy of NK cells, both in models for to combine knowledge on NK cells and preclinical breast cancer models. anti-tumor effect of NK cells will be studied in mouse (PDX) models...

    Maastricht University

    Netherlands 2 days ago

    Add to favorites Read more...

    PhD-Candidate for human intervention studies on (muscle) metabolism within the context of type 2 diabetes

    Type 2 diabetes is a severe chronic disease urgently needing new treatment in Medicine or Biomedical Sciences (or a comparable degree) who is looking small-scale human studies, in which she/he will perform drug and/or lifestyle...