Organoid cell culture specialist (MSc, AC-TAP) In the Wennerberg group, Biotech Research & Innovation Centre (BRIC)

Copenhagen University
February 05, 2023
Contact:N/A
Offerd Salary:Negotiation
Location:N/A
Working address:N/A
Contract Type:fixed-term position
Working Time:Full time
Working type:N/A
Ref info:N/A

Faculty of Health and Medical Sciences

University of Copenhagen

We are looking for a highly skilled and motivated academic staff scientist (MSc) to support ongoing ovarian cancer projects involving organoid culture and establishing an ovarian cancer organoid living biobank.

Our research

The Wennerberg group focuses on identifying drug-resistant subpopulations in ovarian cancer in the framework of precision medicine. Our research models are patient-derived organoids (PDOs) – long-term cultures of patient cells isolated from tumors. We have developed a robust protocol to establish ovarian cancer PDOs from cryopreserved samples and established 17 long-term organoid models, which have been validated to confirm their genetic identity over time. Moreover, we have performed pharmacologic and phenotypic characterizations, and optimized different assays for our organoid platform (Senkowski et al.). Our aim is to understand the phenotypes of the drug-resistant tumor-initiating cells, their mechanisms of drug resistance as well as to identify therapeutic strategies to overcome it.

Your job

You will be a central part of a team of academic scientists composed by 3 post-docs and 2 Ph.D. fellows. Your main task will be to establish new organoid cultures from patient samples and maintain existing cultures while managing the biobank. For that, you will work in close collaboration with the team members and adjust your work to the needs of the team. You will lead the work on preparation and ordering of reagents for organoid culture as well as on culture passaging. In addition to the biobank tasks, you will also contribute to the optimization of our culturing method and to the characterization of organoid models based on patients' clinical information. Finally, you will be expected to contribute to and support the ongoing research projects in the group on an ad hoc basis; disseminate your expertise to new lab members and support the lab management.

Profile

We are looking for a highly motivated and dedicated staff scientist with the following competencies and experience:

Essential experience and skills

  • You have a MSc in life sciences or related
  • You have experience in cell culture of primary cells
  • You have strong organizational skills and a detail-oriented mindset
  • You have strong planning and record-keeping skills
  • You have an open and service-minded attitude
  • You have excellent teamwork and communication skills
  • You have good English skills, written and spoken
  • Desired experience and skills

  • You have a genuine interest in precision medicine and biobanking
  • Experience with organoid culturing
  • Experience in preparation of reagent stocks
  • Experience managing an inventory and ordering reagents
  • Isolation of DNA/RNA
  • Organization and coordination of biobanks
  • Ability to envision, plan and execute projects
  • Place of employment

    The place of employment is at BRIC, University of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. English serves as the working language within the laboratory and BRIC as a whole. Our research facilities include modern laboratories and a number of core facilities shared between the 24 research groups at BRIC and the neighboring Finsen Laboratory.

    Terms of salary and employment

    The employment as Organoid cell culture specialist (staff scientist) is a full time and fixed-term position until February 28, 2025. Starting date is as soon as possible, with March-April, 2023 being the desired start date. Employment will be in accordance with the provisions of the collective agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications. The employer will pay an additional 17.1 % to your pension fund.

    Questions

    For further information regarding the position, please contact Krister Wennerberg; email [email protected]

    Application

    Your application in English should include:

    • Letter of motivation addressing the requirements (max. one page).

    • Curriculum Vitae, including the names and contact information of 2-3 professional references

    • A certified/signed copy of certificate(s) of education

    Please submit your application by clicking on “Apply Now” below. Only online applications will be accepted.

    Application deadline: 5 February 2023 , 23.59 CET

    We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

    Interviews are expected to be held about 1-2 weeks after the application deadline.

    The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background. Appointment will be based on merit alone.

    Suggested 3 weeks after posting

    From this employer

    Recent blogs

    Recent news