MR RESEARCH FACULTY

University of Iowa
March 16, 2023
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MR RESEARCH FACULTY Requisition # 74402 Position Basics Type of Position OTHER

Advertising Ends on: Extended Until Position is Filled Advertising Started on: Wednesday, February 23rd, 2022 College: Carver College of Medicine Department: Radiology

Salary Salary: Commensurate Position Details Full/Part Time Status: Full Time

Position Description:

The Roy J. and Lucille A. Carver College of Medicine Department of Radiology is currently recruiting Assistant(s), Associate(s) Research Track and Assistant Professor(s), Associate Professor(s), or Professor(s) for Tenure Track within the MR Research Facility.

The primary function of this position is to develop a translational Magnetic Resonance (MR) imaging research program focused on neonatal development. The focus of this work will be the assessment of cardiac and brain development across the lifespan in children born prematurely. This position will help to build and optimize clinical imaging protocols as well as develop a translational MR imaging research program. The successful applicant will collaborate extensively with researchers and clinicians, within the Department of Pediatrics, who are considered world leaders in the care of extremely preterm infants born as early as 22 weeks and developmental hemodynamics related to the immature heart and circulation. This position will also have strong collaborations with the Departments of Psychiatry, Neurology, and Cardiology as well as with the MR Research Facility. This position is expected to develop image analysis pipelines for the analysis of anatomical and functional MR imaging data. This includes the development of analysis tools to generate quantitative results from the acquired data and helping optimize existing clinical sequences in cardiac imaging. In addition, this position will report the results from these efforts in scientific publications as well as initiate and support the writing and submission of grant applications. Dependent on candidate, performance-based promotion to a tenure-track faculty position is anticipated in line with the strategic development plan of the program.

The incumbent is expected to work in a fast-paced research environment with diverse team of investigators, students, and staff members. The University of Iowa has state-of-the-art MR facilities including a 1.5T Siemens Aera and 3T Siemens Vida in the Stead Family Children's Hospital as well as research dedicated 3T GE Premier and 7T GE MR950 whole body scanners and a 7T GE MR901 for small animal imaging in the MR Research Facility. The departments of Pediatrics and Radiology have funding to purchase an MRI compatible incubator and are committed to a dedicated NICU MRI. Finally, we have an open bay for the placement of the next generation Siemens PET/MR when that becomes available.

For More Information About Research in the Department of Radiology: https: // medicine.uiowa.edu/radiology/research

The University of Iowa is an equal opportunity/affirmative action employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, national origin, age, sex, pregnancy, sexual orientation, gender identity, genetic information, religion, associational preference, status as a qualified individual with a disability, or status as a protected veteran.

About the MR Research Facility:

The University of Iowa MR Research Facility was established in August of 2004 and now supports research dedicated 3T and 7T whole body scanners and a 7T small animal scanner. The MRRF facility has received two NIH High End Instrumentation grants over the past ten years to help support the acquisition of these instruments. In 2016, the facility moved into the Iowa Institute for Biomedical Imaging (IIBI) located within the Pappajohn Biomedical Discovery Building (PBDB). The MRRF is run as a Core University facility.

The MR Research Center aims to maintain state-of-the-art equipment and facilities. This requires an investment in both the hardware and software that compose our center's mainstay, and also an investment in recruiting and maintaining exceptional personnel. To that end, we have been actively pursuing development in the following areas to advance the research at our University...

Diffusion Tensor Imaging (DTI) - This is of interest mainly for evaluation of brain morphology changes associated with neurological and psychiatric disorders. We have been working on novel schemes for rotating the diffusion tensor and multishot approaches for high resolution Diffusion Tensor Imaging. We are also working on tools for fiber tracking. These tools are currently available through the Neuroimaging Informatics Tools and Resources Clearinghouse.

T1rho Imaging - The primary application of this technique is to assess and quantify pathologic cartilage matrix changes that are not detectable with standard morphological MRI. Initial work has focused on the knee joint in an ACL injury population to determine the suitability of T1rho as an imaging biomarker for early detection of osteoarthritis. Broader application to the ankle and hip joints are also being explored. We are also evaluating the utilization of this method to study pH changes that may result from stress including Post Traumatic Stress Disorder and depression.

Arterial Spin Labeling – Using the Siemens ASL WIP for VB13, we have started to evaluate this technique for functional brain activation studies. To date we have successfully generated reproducible measurements within the occipital cortex and are starting to evaluate higher order cognitive activation studies.

MR Spectroscopy – We have been working on tools for partial volume correction of brain MR spectroscopy studies and have been able to obtain the PEPSI sequence from Stefan Posse. Various pilot studies are currently being conducted using 1H-MRS, and at least one research group has voiced interest in evaluating treatment trials in Huntington's disease using 1H-MRS.

Magnetic Source Imaging – We are currently working on assessing the validity and reliability of magnetic source imaging. This is a potentially powerful tool to understand brain function at a high temporal and spatial resolution.

Pulmonary MRI – Lung imaging research within the MRRF and Department of Radiology encompasses both ultrashort time to echo (UTE) and hyperpolarized 129Xe MRI development. The primary application of these techniques is being developed for clinical translation to understand and improve treatment for chronic lung diseases such as cystic fibrosis, chronic obstructive pulmonary disease, interstitial lung disease and lung transplant.

Cardiac MRI – Cardiac MRI development encompasses novel methods for fast self-gated cardiac motion compensation, including perfusion and wall motion studies in conjunction with 4D Flow measures of blood velocity in major vessels (e.g. aorta and pulmonary artery and venous flow) allowing for characterization of pulmonary arterial hypertension, and congenital heart disease and heart failure.

Dynamic Contrast Enhanced (DCE) MRI – Fast DCE MRI research focuses on chronic diseases leading to impaired regional perfusion and phenotyping of breast cancer lesions using kinetic modeling. Technical development applications include improved acquisition and reconstruction methods for high spatial and temporal resolution fast MRI studies.

Education Requirement:

A Ph.D. in an engineering or science field such as Biomedical Engineering, Electrical Engineering, Chemistry, Physics, or Computer Science is required.

Required Qualifications:

EXPERIENCE REQUIRED

  • Training in MR physics and image acquisition.

  • At least 3 years of experience with medical image analysis.

  • Excellent verbal and written communication skills.

  • Demonstrated strong analytical and data analysis skills.

  • At least 3 years of experience with MRI pulse sequence development.

  • Experience with scripting languages (e.g. Python) for the development of image analysis pipelines.

  • Candidate must be committed to the University's goal of inclusiveness and have a demonstrated history of working effectively with persons of all races, ethnicities, nationalities, genders, gender identities, sexual orientations, and religions.

  • Desirable Qualifications:

    HIGHLY DESIRABLE QUALIFICATIONS

  • Prior postdoctoral training in MR imaging/spectroscopy.

  • Prior research experience with cardiac or brain MR imaging.

  • Prior success with grant applications and peer-reviewed publications.

  • ‪Knowledge of Siemens IDEA and ‪GE EPIC pulse programming environments.

  • Prior experience with ultra-high field MR imaging.

  • Prior experience with cluster computing.

  • Online Application Required Documents

    Curriculum Vitae Name and Contact Information of References Letter of Interest

    Number of References: 3

    To start the Online Application process for this position, click the "Apply for This Position" button located below the Contact Information.

    Contact Information

    Contact: Amie E Stewart - [email protected] VPMA-Human Resources College of Medicine Administration Building 451 Newton Road 302 CMAB Iowa City, IA 52242 Phone: 319-353-6992 Department URL: https: // medicine.uiowa.edu/radiology/

    The University of Iowa is an equal opportunity/affirmative action employer. All qualified applicants are encouraged to apply and will receive consideration for employment free from discrimination on the basis of race, creed, color, religion, national origin, age, sex, pregnancy (including childbirth and related conditions), disability, genetic information, status as a U.S. veteran, service in the U.S. military, sexual orientation, gender identity, or associational preferences. The University also affirms its commitment to providing equal opportunities and equal access to University facilities. Women and Minorities are encouraged to apply for all employment vacancies. For additional information on nondiscrimination policies, contact the Coordinator of Title IX and Section 504, and the ADA in The Office of Institutional Equity, 319/335-0705 (voice) or 319/335-0697 (text), The University of Iowa, 202 Jessup Hall, Iowa City, Iowa, 52242-1316.

    Persons with disabilities may contact University Human Resources/Faculty and Staff Disability Services, (319) 335-2660 or [email protected], to inquire or discuss accommodation needs.

    Prospective employees may review the University Campus Security Policy and the latest annual crime statistics by contacting the Department of Public Safety at 319/335-5022.

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