Organisation/Company: UNIVERSITA' CATTOLICA DEL SACRO CUORE
Research Field: Medical sciences › Medicine
Researcher Profile: First Stage Researcher (R1) Recognised
Researcher (R2) Established Researcher (R3) Leading Researcher (R4)
Application Deadline: 05/10/2022
Type Of Contract: To be defined
Eu Research Framework Programme: FP7
The mammalian target of rapamycin (mTOR) pathway controls cellular growth
and its dysregulation can cause a variety of pathologic conditions,including
various types of human cancers. The tumorigenesis process can be triggered by
alterations affecting components of mTOR pathway, mTOR modulators, such as the
transcription factor TFEB and components of PI3K/Akt pathway, through still
unclear mechanisms. The final goal of this project is to produce knowledge
advancements on the mechanisms underlying mTOR-driven tumorigenesis, which
will ultimately provide insights into potential therapeutic treatments.
Specifically, we will focus on the role of classI PI3K in mTOR activation in
lectin pathway in mouse models of cancer and metastasis using gene targeted
lectin pathway activation and complement deposition using in vitro approaches;
c) the relevance of this pathway through pharmacological targeting; d) its
Research on neural substrates of drug relapse has yet to be translated into
considerations, recently, we have developed a social choice-based rat model of
based voluntary abstinence counteract nucleus accumbens protein translation
Eligible destination country/ies...
Research Field: Biological sciences
Location: France › LYON 08
The CRCL (UMR Inserm 1052 – CNRS 5286 – Centre Léon Bérard) is a cancer
research structure certified by the University of Lyon 1, Inserm, the...
Research Field: Medical sciences
Location: Italy › Bologna
minimal residual disease after an effective treatment.
bispecific antibodies in patients with heavily pretreated B-cell lymphomas;
patients with hairy cell leukemia and correlation with overall survival and...
agonist for the therapy of narcolepsy type 1, which is presently in the
address: https: // bandi.unibo.it/ricerca/assegni-ricerca
Eligible destination country/ies for fellows:
Eligibility of fellows: country/ies of residence:
https: // bandi.unibo.it/ricerca/assegni-ricerca
Organisation Type: Public Research...
The main causes of chronic kidney disease are diabetes mellitus,
Chronic kidney disease causes numerous problems throughout the body.
kidneys suffering from chronic kidney disease produce hormones that increase
each other by accelerating the progression...