Mechanisms And Role Of Mtor Hyperactivation In Cancer.

Universities and Institutes of Italy

Italy

October 5, 2022

Description

  • Organisation/Company: UNIVERSITA' CATTOLICA DEL SACRO CUORE
  • Research Field: Medical sciences › Medicine
  • Researcher Profile: First Stage Researcher (R1) Recognised Researcher (R2) Established Researcher (R3) Leading Researcher (R4)
  • Application Deadline: 05/10/2022
  • Location: Italy
  • Type Of Contract: To be defined
  • Eu Research Framework Programme: FP7
  • The mammalian target of rapamycin (mTOR) pathway controls cellular growth and its dysregulation can cause a variety of pathologic conditions,including various types of human cancers. The tumorigenesis process can be triggered by alterations affecting components of mTOR pathway, mTOR modulators, such as the transcription factor TFEB and components of PI3K/Akt pathway, through still unclear mechanisms. The final goal of this project is to produce knowledge advancements on the mechanisms underlying mTOR-driven tumorigenesis, which will ultimately provide insights into potential therapeutic treatments. Specifically, we will focus on the role of classI PI3K in mTOR activation in colorectal cancer.

    Eligibility criteria

    Eligible destination country/ies for fellows:

  • Italy
  • Eligibility of fellows: country/ies of residence:

  • EUROPE
  • Eligibility of fellows: nationality/ies:

  • EUROPE
  • Web site for additional job details

    https:// progetti.unicatt.it/progetti-ateneo-roma-assegni-di-ricerca- legge-240-...

    Contact Information
  • Organisation/Company: UNIVERSITA' CATTOLICA DEL SACRO CUORE
  • Organisation Type: Private with public mission
  • Website: https:// progetti.unicatt.it/progetti-ateneo-roma-assegni-di- ricerca-legge-240-...
  • Country: Italy
  • City: ROMA
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