MD-PhD or PhD student
The Institute for Infectious Diseases performs tasks in teaching and research
as well as in diagnostic microbiology in the fields of virology, bacteriology,
mycology, parasitology and serological infection clarification. It is the only
university institute in Switzerland that combines all microbiological
specialties in the field of clinical microbiology under one roof. In the
framework of the newly founded Multidisciplinary Center for Infectious
Diseases we are offering a MD-PhD or PhD student position.
Confronting the rising epidemic of the zoonotic tick-borne encephalitis virus
Causative treatment options for tick-borne-encephalitis (TBE), a severe
neurological disease, associated with mortality and long-lasting consequences
are lacking. We hypothesize that the diseases severity is determined by the
ability of the TBE virus to replicate in different cells types of the CNS and
to induce a detrimental host-driven immune reaction.
In the project we will use complementary approaches including rodent brain
organotypic cultures complemented with an experimental model of TBE in rats.
The efficient screening and validation of potential antiviral molecules
represents an additional objective of the project that will be performed in
close collaboration with the group of PD. Marco Alves, Institute of Virology
and Immunology in Bern, involving one Ph.D student at each site.
Technologies involved during the project: organotypic cultures, experimental
rodent model of viral encephalitis, microbiology, histology, transcriptomics,
immunofluorescence, inflammatory parameter determination.
The applicant must hold a master degree in cell biology, neurology, medicine
or microbiology from a Swiss University (or equivalent), have a high
motivation to succeed in science and be willing to acquire expertise in
experimental models of infectious disease, central nervous system damage,
immune system and inflammation. For this project, the candidate must provide
an outstanding ability to work in collaborative environment involving
different laboratory and partners. Further, it is mandatory for the candidate
to be able to comply with strict laboratory procedures at a biosafety level 3.
Previous experience with animal experimentation in rodents, including FELASA
license or equivalent is an asset.
The Institute for Infectious Diseases, University of Bern provides an
international working atmosphere with regular seminars in English language and
offers modern laboratory equipment and a multidisciplinary setting. The
candidate will be trained to work with rodents and pathogenic microorganisms.
Results of research will be presented by the PhD student at international
meetings. The student will be enrolled in the Graduate School for Cellular and
Biomedical Sciences of the University of Bern (www. gcb.unibe.ch). Salary
will be according to the guidelines of the Swiss National Science Foundation.
Information about the application:
Immediately or according to agreement
Motivated applicants are encouraged to send their CV, copies of grades,
diplomas and letters of references as digital files (preferred format is
.pdf) until January 07th 2022 exclusively to: email@example.com
For more details: www. ifik.unibe.ch
https: // www. ifik.unibe.ch/forschung/neuroinfectionlabstephenleibdennisgrandgirard/indexger.html
https: // www. mcid.unibe.ch/
Institute for Infectious Diseases, University of Bern, CH-3001 Bern
Phone: +41 31 632 78 63