Design, synthesis and characterisation of dendrimeric nanosystems for
The candidate will design, synthesize, characterize and evaluate different
functional dendrimers for the delivery of nucleic acid therapeutics and
anticancer drugs in immunotherapy against the glioblastoma. The size,
morphology, stability and capacity of these dendrimer nanosystems to transport
nucleic acid and anticancer drug will be studied using DLS, TEM, HPLC and
fluorescent spectroscopy. Their delivery efficacy will be evaluated in vitro
using cell-based experiment and in vivo using animal models. Also a structure-
activity relationship study will be released to optimize the dendrimer
nanosystems for nucleic acid delivery.
Synthesis of dendrimers for nucleic acid and drug delivery
The candidate will design, synthesize and characterize different dendrimers
for the delivery of nucleic acid therapeutics and anticancer drugs for
immunotherapy against glioblastoma. This project is within a collaborative and
interdisciplinary research consortium under the frame of H2020 Era-Net
EuroNanoMed project “iNanoGUN”.
Motivated candidates with team-work spirit and background in nucleic acid
delivery are welcome to apply.
Please submit online a single PDF file with detailed CV including education
and work experience, summary of PhD thesis (1 page maximum) and post-doc
research (1 page maximum) and at least two reference letters of the
As a joint research institute of CNRS and Aix-Marseille University, CINaM is
composed of about 150 people and 5 departments and is located on the Luminy
Campus in Marseille (France).
The recruited person will work in the group of Dr. Ling PENG in the Department
of Molecular Engineering and Functional Materials (IMMF). This department is
made up of 21 researchers and teacher-researchers, mainly chemists. English
speaking is mandatory.
- Design, synthesis and characterization of dendrimers for biomedical
- Solid basic theory and good practical experience for organic synthesis
- Independent working and team working capacity
- Good communication and writing skill in English
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