The Life Science Research Professional 2 (LSRP2) position will provide the
ideal candidate an opportunity to manage a lab of 8 to 10 members, support
different research projects, and work closely with the PI and team of staff in
the Division of Gastroenterology, Hepatology, and Nutrition within the
Department of Pediatrics. The Husain Lab's primary goals and investigative
programs are to decipher the crucial signaling pathways that initiate and
transduce pancreatitis, identify the factors that turn on pancreatic
regeneration and recovery after pancreatic injury, and elucidate the
mechanisms underlying specific forms of drug-induced pancreatitis (DIP)
using genetic approach and stem cell transplantation strategies in combination
with confocal microscopy, metabolomics, and spatial transcriptomics. The
ultimate goal is to develop novel therapeutic and diagnostic approaches for
both pediatric and adult pancreatic diseases and disorders.
The successful applicant will have BS or MS degree in Biology, Cell and
Molecular Biology, Immunology, or a related field is required, and at least 2
years of experience (including both research and management experience) in a
relevant laboratory setting with basic computational skills to import data
sets and explore simple relationships using basic data visualization tools,
and run basic formal statistical tests. The Husain Lab strives to create a
highly collaborative, dynamic and positive environment that fosters
intellectual curiosity and passion for the discovery of new knowledge.
Learn more about our lab here: https: // www. husainlab.org
Duties and roles include:
Independently conduct a portion of the research project(s). Make
recommendations on experimental design and/or research direction to
Keep LIMS (laboratory information management system) updated and record
all methods and results from all lab projects including using Excel,
GraphPad Prism and others.
Independently conduct complex (lab and/or field) experiments to gather
data for a portion of a major research project, including establishing
transgenic mouse colony and genotyping.
Interpret and analyze results, often where few guidelines exist, and make
modifications to existing procedures and protocols.
Develop new research protocols where appropriate protocols are not
described in the literature or where modification or adaptation of
standard procedures and protocols is required.
Participate in multidisciplinary teams across different faculties or
Perform ongoing literature review to remain current with new procedures
and related research; apply to ongoing research and development of new
Contribute substantively to the preparation of papers for publication,
especially in the results section, and to publication of findings. Present
ongoing work to colleagues and/or academic conferences.
Oversee supply and equipment budget under supervision of principal
investigator or business manager.
Work with health and safety department to ensure lab complies with
regulations and all required trainings.
Supervise (either formally or informally) staff or students as needed,
including oversight and direction on techniques, as well as consultation
on project work. Serve as a technical resource for other research staff.
Oversee the daily activities of the laboratory including lab maintenance;
maintain lab stock, manage animal inventory, manage chemical inventory and
safety records, and provide general lab support as needed. May assist with
purchasing laboratory equipment.
Experience with mouse and human cell lines and primary cell culture, mouse
surgical procedures and necropsy, immunohistochemistry, western blot,
laser confocal/3D imaging, flow cytometry and FACS, CRISPR gene editing,
and PCR and qPCR, is highly desired.
Experience with lab management, including hand-on experience with LIMS
(laboratory information management system) and research protocols
(involving animal and/or human participants), is highly desired
Basic computational and programming skills are desired.
Exceptional attention to detail and meticulous execution and record of
experiments is essential.
Must be able to think critically and is able to design experiments,
interpret results, troubleshoot, and optimize experimental protocols
independently or with limited guidance.
EDUCATION & EXPERIENCE (REQUIRED): Bachelor's degree in biology, cell
and molecular biology, or a related scientific field and two or more years of
relevant work experience; or Master's degree in a related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
Comprehensive understanding of scientific principles.
General computer skills and ability to quickly learn and master computer
programs, databases, and scientific applications.
Strong analytical skills and excellent judgment.
Ability to maintain detailed records of experiments and outcomes.
Ability to work under deadlines with general guidance is essential.
Excellent organizational skills and demonstrated ability to accurately
complete detailed work.
CERTIFICATIONS & LICENSES: Not required
Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine
manipulation, grasp forcefully, perform desk-based computer tasks, use
telephone, write by hand, lift, carry, push and pull objects weighing over
Occasionally sit, kneel, crawl, reach and work above shoulders, sort and
file paperwork or parts.
Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot
Must have correctible vision to perform duties of the job.
Ability to bend, squat, kneel, stand, reach above shoulder level, and move
on hard surfaces for up to eight hours.
Ability to lift heavy objects weighing up to 50 pounds.
Ability to work in a dusty, dirty, and odorous environment.
Position may require repetitive motion.
Add or subtract physical requirements based on the requirements of your
specific job. (remove this statement for posting)
- Consistent with its obligations under the law, the University will
provide reasonable accommodation to any employee with a disability who
requires accommodation to perform the essential functions of his or her job.
May require working in close proximity to blood borne pathogens.
May require work in an environment where animals are used for research.
Position may at times require the employee to work with or be in areas
where hazardous materials and/or infectious diseases are present.
Employee must perform tasks that require the use of personal protective
equipment, such as safety glasses and shoes, protective clothing and
gloves, and possibly a respirator.
May require extended or unusual work hours based on research requirements and