Junior Scientists Preclinical Immuno-Oncology

Universities and Institutes of France

France

October 17, 2022

Description

  • Organisation/Company: Skymab Biotherapeutics
  • Research Field: Biological sciences › Biological engineering Biological sciences › Biology
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 17/10/2022 00:00 - Europe/Brussels
  • Location: France › Saclay
  • Type Of Contract: Permanent
  • Job Status: Full-time
  • Offer Starting Date: 17/10/2022

  • He/she will assist the Chief Scientific Officer and R&D collaborators in the execution of the experimental plan in close interactions with the R&D Project Manager and CEO.

  • The main role of the position will consist in building the preclinical data package to provide PoC and MoA of immune-mediated ADC activities, which will support the clinical therapeutic claims of the main Skymab candidate.
  • He/she will also contribute to move Skymab second candidate to the clinical development path and build the discovery pipeline of anti-GPCR antibodies and ADCs of Skymab.
  • He/she will contribute with his/her R&D colleague to establish the first R&D laboratory of Skymab within the context of a collaboration with the CEA..
  • He/she will develop and manage in-house R&D activities involving CEA collaborators/platforms as well as externalized R&D activities with CROs, private and academic partners with the support of the CSO and the R&D project manager.
  • Offer Requirements Specific Requirements
  • A PhD degree with experience in preclinical immuno-oncology models and tumor immunology.
  • Mastery of the immunological analysis techniques (eg. FACS, T-cell assays, ELISA, molecular biology techniques…) with murine and human cells
  • Experience in basic biochemical and modern molecular techniques
  • Experience in preclinical in vitro cell-based assay and in vivo oncology models (CDX, PDX, PDXO…), PoC, PK/PD, preclinical validation and characterization of therapeutic antibody candidates and ideally of ADCs is an asset.
  • Proficiency with computing tools and software programs, eg. Prism, Geneious, Sequencher…
  • Meeting the criteria of “Jeune Docteur” of the French Ministry for Higher Education and Scientific Research is a strong asset
  • Experience and certification in animal experimentation (murine species) is an asset
  • Experience in antibody engineering and with bioinformatics tools is a plus
  • Experience or good understanding of GPCR biology is a plus
  • Previous experience in R&D in industry and people management is a plus
  • Contact Information
  • Organisation/Company: Skymab Biotherapeutics
  • Organisation Type: Small Medium Enterprise, Start-up
  • Website: https: // skymab-biotherapeutics.com/
  • Country: France
  • Similar Jobs

    Add to favorites Read more...

    Principal Scientists Preclinical Pharmaco-Immuno-Oncology

    He/she will also contribute to move Skymab second candidate to the clinical experience in in vivo pharmacology and preclinical oncology Experience in immuno-oncology models is an asset Experience in preclinical in vitro cell-based assay and...

    Add to favorites Read more...

    Post Doctoral Researcher

    Research Field: Biological sciences › Biology Medical sciences › Location: France › CRETEIL The BNMS-RELAIX team has a long-standing interest in skeletal muscle stem stem cell targeted therapies using rat preclinical models of Duchenne Muscular...

    Add to favorites Read more...

    Engineer In Molecular And Cell Biology

    Research Field: Biological sciences › Biology Medical sciences We are expanding our Research team and seek an Engineer in Molecular and Cell The R&D engineer is a member of the Research team. communication during Research...

    MRC London Institute of Medical Sciences

    United Kingdom 2 days ago

    Add to favorites Read more...

    Metabolomics Scientist – Proteomics and Metabolomics Facility – LMS 1954

    MRC LMS Proteomics and Metabolomics Facility We are seeking to recruit a metabolomics scientist to work within the LMS innovative metabolomics techniques and work with leading LMS research groups The successful candidate will join the...