He/she will assist the Chief Scientific Officer and R&D collaborators in
the execution of the experimental plan in close interactions with the R&D
Project Manager and CEO.
The main role of the position will consist in building the preclinical
data package to provide PoC and MoA of immune-mediated ADC activities,
which will support the clinical therapeutic claims of the main Skymab
He/she will also contribute to move Skymab second candidate to the
clinical development path and build the discovery pipeline of anti-GPCR
antibodies and ADCs of Skymab.
He/she will contribute with his/her R&D colleague to establish the first
R&D laboratory of Skymab within the context of a collaboration with the
He/she will develop and manage in-house R&D activities involving CEA
collaborators/platforms as well as externalized R&D activities with CROs,
private and academic partners with the support of the CSO and the R&D
Offer RequirementsSpecific Requirements
A PhD degree with experience in preclinical immuno-oncology models and
Mastery of the immunological analysis techniques (eg. FACS, T-cell
assays, ELISA, molecular biology techniques…) with murine and human cells
Experience in basic biochemical and modern molecular techniques
Experience in preclinical in vitro cell-based assay and in vivo oncology
models (CDX, PDX, PDXO…), PoC, PK/PD, preclinical validation and
characterization of therapeutic antibody candidates and ideally of ADCs is
Proficiency with computing tools and software programs, eg. Prism,
Meeting the criteria of “Jeune Docteur” of the French Ministry for Higher
Education and Scientific Research is a strong asset
Experience and certification in animal experimentation (murine species)
is an asset
Experience in antibody engineering and with bioinformatics tools is a plus
Experience or good understanding of GPCR biology is a plus
Previous experience in R&D in industry and people management is a plus
Organisation/Company: Skymab Biotherapeutics
Organisation Type: Small Medium Enterprise, Start-up
He/she will also contribute to move Skymab second candidate to the clinical
experience in in vivo pharmacology and preclinical oncology
Experience in immuno-oncology models is an asset
Experience in preclinical in vitro cell-based assay and...
Research Field: Biological sciences › Biology Medical sciences ›
Location: France › CRETEIL
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Research Field: Biological sciences › Biology Medical sciences
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MRC LMS Proteomics and Metabolomics Facility
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innovative metabolomics techniques and work with leading LMS research groups
The successful candidate will join the...