Junior Scientists Preclinical Immuno-Oncology

Universities and Institutes of France


October 17, 2022


  • Organisation/Company: Skymab Biotherapeutics
  • Research Field: Biological sciences › Biological engineering Biological sciences › Biology
  • Researcher Profile: First Stage Researcher (R1)
  • Application Deadline: 17/10/2022 00:00 - Europe/Brussels
  • Location: France › Saclay
  • Type Of Contract: Permanent
  • Job Status: Full-time
  • Offer Starting Date: 17/10/2022

  • He/she will assist the Chief Scientific Officer and R&D collaborators in the execution of the experimental plan in close interactions with the R&D Project Manager and CEO.

  • The main role of the position will consist in building the preclinical data package to provide PoC and MoA of immune-mediated ADC activities, which will support the clinical therapeutic claims of the main Skymab candidate.
  • He/she will also contribute to move Skymab second candidate to the clinical development path and build the discovery pipeline of anti-GPCR antibodies and ADCs of Skymab.
  • He/she will contribute with his/her R&D colleague to establish the first R&D laboratory of Skymab within the context of a collaboration with the CEA..
  • He/she will develop and manage in-house R&D activities involving CEA collaborators/platforms as well as externalized R&D activities with CROs, private and academic partners with the support of the CSO and the R&D project manager.
  • Offer Requirements Specific Requirements
  • A PhD degree with experience in preclinical immuno-oncology models and tumor immunology.
  • Mastery of the immunological analysis techniques (eg. FACS, T-cell assays, ELISA, molecular biology techniques…) with murine and human cells
  • Experience in basic biochemical and modern molecular techniques
  • Experience in preclinical in vitro cell-based assay and in vivo oncology models (CDX, PDX, PDXO…), PoC, PK/PD, preclinical validation and characterization of therapeutic antibody candidates and ideally of ADCs is an asset.
  • Proficiency with computing tools and software programs, eg. Prism, Geneious, Sequencher…
  • Meeting the criteria of “Jeune Docteur” of the French Ministry for Higher Education and Scientific Research is a strong asset
  • Experience and certification in animal experimentation (murine species) is an asset
  • Experience in antibody engineering and with bioinformatics tools is a plus
  • Experience or good understanding of GPCR biology is a plus
  • Previous experience in R&D in industry and people management is a plus
  • Contact Information
  • Organisation/Company: Skymab Biotherapeutics
  • Organisation Type: Small Medium Enterprise, Start-up
  • Website: https: // skymab-biotherapeutics.com/
  • Country: France
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