Gene Replacement For Cdkl5 Deficity Disorder

Universities and Institutes of Italy

Italy

September 23, 2021

Description

  • Organisation/Company: ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA -
  • DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
  • Research Field: Neurosciences
  • Researcher Profile: First Stage Researcher (R1) Recognised Researcher (R2) Established Researcher (R3) Leading Researcher (R4)
  • Application Deadline: 23/09/2021 23:59 - Europe/Brussels
  • Location: Italy
  • Type Of Contract: To be defined
  • CDKL5 disorder is a rare, severe neurodevelopmental disorder that mostly affects girls. CDKL5 patients show a range of phenotypes including seizures that begin in the first few months of life, visual impairment, gastrointestinal difficulties, mental retardation and autism. They are unable to walk, talk or feed themselves. Currently, there is no cure or effective treatment for CDKL5 disorder, and the mainstay of care for this disorder is support for the families. Therefore, identification of therapies for CDKL5 disorder will represent an important social challenge. The goal of this project is to investigate the potential for gene therapy in CDKL5 disorder. Specifically, the project will involve the development and testing of gene therapy vectors in a mouse model of CDKL5 disorder that ameliorate/correct the neurodevelopmental alterations that characterize the CDKL5 deficient brain.

    Eligibility criteria

    to apply for research grants fill out the form available at the following address: https: // bandi.unibo.it/ricerca/assegni-ricerca

    Eligible destination country/ies for fellows:

  • Italy
  • Eligibility of fellows: country/ies of residence:

  • All
  • Eligibility of fellows: nationality/ies:

  • All
  • Web site for additional job details

    https: // bandi.unibo.it/ricerca/assegni-ricerca

    Contact Information
  • Organisation/Company: ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA -
  • DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
  • Organisation Type: Public Research Institution
  • Website: https:// www. unibo.it
  • Country: Italy
  • City: Bologna
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