BMA/ Laboratory- /Research Engineer to Center for Translational Genomics

Lund University

Sweden

December 12, 2021

Description

Lunds universitet, Medicinska fakulteten, Inst för laboratoriemedicin

Lund University was founded in 1666 and is repeatedly ranked among the world's top 100 universities. The University has around 44 000 students and more than 8 000 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

The Research Group The Center for Translational Genomics (CTG) is a prioritized research infrastructure at the Faculty of Medicine, Lund University, part of the Clinical Genomics platform at SciLifeLab. The platform aims to offer translational and clinical researchers access to state-of-the-art methods in genomics and transcriptomics (e.g. WGS, RNA-seq and new single cell analyses) and to quickly translate new research findings into improved clinical utility in close collaboration with the regional healthcare. Locally, this is performed through close interactions with the Section for Molecular Diagnostics at Region Skåne. Within CTG, there is great expertise in Next Generation Sequencing (NGS) technologies, bioinformatics and several different disease areas, and seen from both a national and international perspective, the unit is at the technological forefront with access to very powerful sequencing instruments (e.g.Illumina NovaSeq 6000). For data processing, the center uses a dedicated high-performance computing cluster at Lund University.

At the national level, CTG and Clinical Genomics Lund are also involved in a Swedish initiative for precision medicine; Genomic Medicine Sweden, where the development of new methods for tomorrow's research and diagnostics is coordinated with the corresponding large-scale sequencing facilities at the country's other university hospitals.

We are now looking for a driven, knowledgeable and service-oriented person, who wants to contribute to front-line research based on advanced genomics methods. The employment is a permanent full-time position with the desired start date of January 1, 2022, or by agreement. Probationary employment of 6 months may be applied.

Work duties and area of expertise You will be part of a lab team of 5-6 people, within which you will primarily focus on services to research projects in need of genomic interrogation methods. Protocols may originate from DNA from both human tissues and from microorganisms and be both comprehensive (e.g. whole genome sequencing) and targeted (e.g. gene panel sequencing based on hybrid-capture enrichment chemistries).

The main tasks include:

  • project planning and execution - i.e. library preparation and sequencing - of established methods within CTG's standard genomics services (e.g. whole genome or gene panel sequencing), with sequencing primarily performed on the Illumina platform (e.g. on the NovaSeq 6000).
  • making project-specific cost calculations for service projects based on established templates
  • customer contact in connection with sample submission prior to quality control, library preparation and sequencing
  • participating in laboratory development of new methods, e.g. for analysis of cell-free tumor DNA (ctDNA)
  • documenting and streamlining of laboratory workflows
  • various administrative tasks, e.g. ordering reagents and laboratory accessories
  • Qualifications The position requires:

  • Adequate University degree, e.g. bachelor's degree as a biomedical analyst or master's degree in molecular biology, biomedicine or equivalent
  • 2 years of documented practical experience in molecular biology (e.g. extraction of DNA/RNA, PCR-based methods, Sanger sequencing, and/or NGS)

  • Very good understanding of and/or previous practical experience in preparing NGS libraries
  • Very good understanding of and/or previous practical experience of sequencing NGS libraries on the Illumina sequencing platform
  • Excellent abilities to quickly learn new methods and establish new protocols
  • Excellent oral and written communication skills in English
  • Great emphasis will be placed on personal suitability. The tasks require that you are structured and have an excellent ability to prioritize at work. The work is team-based - both internally and externally - and therefore requires very good communication and collaboration skills. In addition, you need to have the ability to work independently. We are looking for you who are unpretentious and have a service-oriented approach.

    The following are desired for the position:

  • PhD in a relevant field (e.g. genomics or genetics)
  • 2 years of practical experience of methods based on NGS (library preparation and/or sequencing)

  • Experience in working with liquid handling systems for automation of laboratory protocols
  • Experience in single cell sequencing methods (e.g. based on the 10X Genomics platform) and/or from tissue-based analysis
  • Excellent oral and written communication skills in Swedish
  • Instructions for your application The application must contain a personal letter describing how you fulfill the desired qualifications, a CV and diploma.

    Other The university applies individual salary setting. Please indicate your salary claim in your application.

    The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty's strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

    The Department of Laboratory Medicine is one of six departments at Lund University's Faculty of Medicine. We conduct leading research, both broad and specialised, within the field of laboratory medicine, focusing on the onset of disease and how we can improve diagnostics and treatment for patients. Some of our strongest areas with world-class research deal with cancer, genetics and blood.

    We kindly decline all sales and marketing contacts.

    Type of employment Permanent position

    Contract type Full time Number of positions 1 Working hours 100 City Lund County Skåne län Country Sweden Reference number PA2021/3640 Contact

  • Markus Heidenblad, rekryterande chef, 046-2220000
  • Emelie Falck, personalsamordnare, 046-2220000
  • Published 25.Nov.2021 Last application date 12.Dec.2021 11:59 PM CET

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