Lawrence Berkeley National Lab's (LBNL), Environmental Genomics and Systems
Biology (EGSB) Division has an opening for a Biologist Postdoctoral Fellow.
The Postdoc will work as part of a team to develop and apply experimental
methods to isolate novel phages, integrate recent advances in genome-wide
screening technologies to study host-phage interaction determinants, leverage
mining of viral metagenomic and metatranscriptomic datasets to ecologically
contextualize new isolates, and attempt to engineer host determining factors
in the novel phages. Success of this project will lay the foundation towards
establishing innovative methods to isolate, characterize and engineer atypical
phages and can be focused to support the agricultural, environmental and
health strategies of Berkeley Lab. The work will be conducted in collaboration
with scientists from the EGSB Division and Joint Genome Institute (JGI).
What You Will Do:
Develop a standardized workflow to enrich and isolate atypical phages
for non-model bacteria.
Establish characterization methods to study phage interaction with
diverse bacteria and analyze metagenomic and metatranscriptomic data for
Develop and perform high-throughput genetics and physiological screening
to determine gene function.
Working with the team to identify new mechanisms of host-phage
specificity, infection, defense, and reproduction from this high
Use this information to build chimeric phages and engineer phages with
Additional Responsibilities as needed:
Prepare research results for publication and for presentations at
scientific and internal meetings.
Maintain an accurate and detailed scientific logbook of all experiments
performed. Archive generated material (plasmids / strains / phages).
Ensure that others could duplicate results.
What is Required:
PhD in microbiology, virology, biochemical engineering, synthetic
biology, genomics, or molecular biology.
Experience with phage isolation, phage sample handling,
characterization, and phage engineering.
Experience in high-throughput synthetic biology.
Experience in microbial physiology and genetics.
Knowledge of next generation sequencing technologies.
Outstanding writing and oral communication skills, maintain appropriate
records and manage data.
Independent but collaborative mindset with excitement in solving
problems and exploring/characterizing novel micro-organisms.
Experience in molecular biology (cloning).
Comfortable to write scripts in at least one programming language
(bash, perl, python, etc.).
Experience in handling and analysis of large datasets.
Experience with bioinformatic analysis of novel phage genomes.
This is a full-time1 year, postdoctoral appointment with the possibility
of renewal based upon satisfactory job performance, continuing
availability of funds and ongoing operational needs. You must have less
than 3 years of paid postdoctoral experience. Salary for Postdoctoral
positions depends on years of experience post-degree.
This position is represented by a union for collective bargaining
Salary will be predetermined based on postdoctoral step rates.
This position may be subject to a background check. Any convictions will
be evaluated to determine if they directly relate to the responsibilities
and requirements of the position. Having a conviction history will not
automatically disqualify an applicant from being considered for
Diversity, equity, and inclusion are core values at Berkeley Lab. Our
excellence can only be fully realized by faculty, students, and staff who
share our commitment to these values. Successful candidates for our
faculty positions will demonstrate evidence of a commitment to advancing
equity and inclusion.
Work will be primarily performed at: West Berkeley Biocenter (Potter
St.) — Bldg. 977, 717 Potter St., Berkeley, CA.
Learn about us!
Environmental Genomics and Systems Biology
Mission: Linking genome biology to ecosystem dynamics.
Vision: Sustainable solutions to energy and environmental challenges
developed through mechanistic understanding of ecosystem dynamics.
Approach: We develop systems-level models using integrated molecular
observation and controlled manipulation of model organisms and defined biomes
to design and test interventions that promote beneficial outcomes.
Berkeley Lab (LBNL) addresses the world's most urgent scientific
challenges by advancing sustainable energy, protecting human health, creating
new materials, and revealing the origin and fate of the universe. Founded in
1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel
prizes. The University of California manages Berkeley Lab for the U.S.
Department of Energy's Office of Science.
Working at Berkeley Lab has many rewards including a competitive
compensation program, excellent health and welfare programs, a retirement
program that is second to none, and outstanding development opportunities. To
view information about the many rewards that are offered at Berkeley Lab-
Equal Employment Opportunity: Berkeley Lab is an Equal
Opportunity/Affirmative Action Employer. All qualified applicants will receive
consideration for employment without regard to race, color, religion, sex,
sexual orientation, gender identity, national origin, disability, age, or
protected veteran status. Berkeley Lab is in compliance with the Pay
Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to
view the poster and supplement: "Equal Employment Opportunity is the Law."
Lawrence Berkeley National Laboratory encourages applications from women,
minorities, veterans, and other underrepresented groups presently considering
scientific research careers.