Assistant Professor (Post-Doc) At The Department Of Chemical Biology At The Faculty Of Biotechnology

Universities and Institutes of Poland
December 23, 2022
Contact:N/A
Offerd Salary:Negotiation
Location:N/A
Working address:N/A
Contract Type:Temporary
Working Time:Full time
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Job Ref.:N/A
  • Organisation/Company: University of Wroclaw
  • Research Field: Medical sciences
  • Researcher Profile: Recognised Researcher (R2)
  • Application Deadline: 23/12/2022 23:00 - Europe/Brussels
  • Location: Poland › 50-137 Wrocław
  • Type Of Contract: Temporary
  • Job Status: Full-time
  • Hours Per Week: Tbd
  • Offer Starting Date: 01/02/2023
  • University of Wroclaw invites applications for the position of assistant professor (post-doc) at the Department of Chemical Biology at the Faculty of Biotechnology

    No 116.2022.ZChB.WB of November 23, 2022

    Institute/Department: Faculty of Biotechnology

    Position: assistant professor (post-doc)

    Type of position: research

    Research area / discipline: medical sciences, biomedical engineering

    Vacancies/positions: 1

    Application deadline: December 23, 2022

    Expected contest results: January, 2023

    Envisaged job starting date: February 1, 2023

    Employment period: one year (possible extension to three years)

    Type of contract: full time

    Salary monthly: 7296 -7608 brutto PLN

    Applications are invited from those who fulfil the statutory requirements specified in the Higher Education Act from 20th July 2018 (Dz. U. z 2018 r., poz. 1668) and the statutes of the University of Wroclaw.

    Expectations:

  • PhD in chemical, biological sciences or in related disciplines.
  • Scientific achievements documented by publications and implemented projects.
  • Experience in recombinant protein expression and purification.
  • Experience in metalloproteins research is highly appreciated.
  • Knowledge of modern spectroscopic techniques, including mass spectrometry.
  • Ability to present achievements confirmed by documented presentations at the national or international forum Active participation in conferences, workshops, courses and other forms of supporting scientific development.
  • Proficiency in written and spoken English.
  • Motivation to scientific work.
  • Ability to work independently and in a team.
  • Participation in scientific meetings.
  • Preparation of scientific publications.
  • Active participation in scientific conferences.
  • Responsibilities:

  • In the research area:

  • conducting experiments, results analysis, regular record keeping according to common standards

  • daily work in the science laboratory and good cooperation with other members of the research team
  • Preparation of reports, presentations and publications.

  • In the organizational area:

  • participation in faculty/department meetings

  • seminars, preparing publications
  • active participation in conferences
  • Employment under the National Science Center project of the OPUS project of the National Science Center (2021/43 / B / NZ1 / 02961), under the title " Structure and role of copper-zinc metallothioneins in the cellular buffering of copper and zinc ions ".

    The principal investigator of the project is professor Artur Krężel.

    The project concerns determining the mechanisms of the functioning of metallothioneins (a family of low-molecular polycysteine cellular proteins) as a molecular linker in the cellular homeostasis of zinc and copper ions. Zinc and copper are two essential metal micronutrients of the d-block, which in inorganic biochemistry are often treated independently, for example, due to redox properties, mode of transport, and cellular distribution. However, both metals are bound by metallothioneins, although the role of these proteins in copper binding is not fully understood. On the other hand, it is known that metallothioneins are crucial for ensuring an adequate level of these metals in the cell and are responsible for the proper functioning of numerous signaling pathways dependent on zinc and copper. Dysfunction of these pathways leads to numerous disorders resulting in pathogenic changes, including cancer. Metallothioneins (MT), although studied for years in terms of chemical and biochemical characteristics, have always been treated as homogeneous proteins saturated only with zinc, copper, or cadmium (spectroscopic zinc probe). However, more and more biological evidence indicates the essence of mixed complexes with zinc and copper. Therefore, the present project is about understanding the properties, structure, and stability and, above all, explaining the role of mixed Cu / Zn-MT complexes in the homeostasis of these two elements. We plan, among others explain whether the mixed forms of MT control the level of both elements independently of each other or whether they are proteins that connect the metabolism of these metals. Furthermore, the project aims to determine how the mixed forms of MT regulate the function of other zinc and copper-dependent proteins and the consequences of dysfunction of this regulation.

    Our team has extensive experience working on metalloproteins, determining their structure, stability, and mechanisms of (un)folding and interaction with other biomolecules. We offer work on unique and very modern research equipment and a chance to learn about a wide range of techniques in spectroscopy, mass spectrometry, biological chemistry, molecular biology, peptide synthesis, protein production, and purification and to present our results at international scientific conferences.

  • Curriculum vitae.
  • Personal questionnaire (PERSONAL DATA FORM FOR EMPLOYMENT APPLICANT).
  • A photocopy of the diploma confirming obtaining the academic degree of doctor.
  • Statement whether the University of Wroclaw will be the primary place of work in the case of winning the competition (Workplace statement UWr).
  • Declaration of the discipline in which the candidate will conduct research, and in the case of people conducting research in more than one discipline, the percentage of their involvement in each of these disciplines (Scientific discipline declaration UWr).
  • Self-presentation (information about scientific, organizational, and other achievements).
  • List of scientific publications in the last ten years.
  • Electronic versions of the two most important publications that the candidate considers representative of his or her scientific achievements, or an explanation of the lack of them, provided that the Chairman of the Committee may expect all or selected scientific publications or other documents to be submitted.
  • Two recommendation letters sent by well-known specialists in the area of experimental nuclear physics or solid state physics, provided that these letters are sent by e-mail to the Chairman of the Competition Committee at artur.krezel@uwr.edu.pl, without the candidate's mediation and are open only to members of the Committee, and the candidate, by entering the competition, waives the right to access these lists.
  • CV should include the following note : I consent, within the meaning of Articles 4 and 7 of RODO, i.e. Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation) (Official Journal of the EU L of 4.05.2016, pp. 1-88), to the processing of my personal data by the University of Wroclaw, pl. Uniwersytecki 1, 50-137 Wroclaw, for the purpose of recruitment for employment at the University of Wroclaw. I am aware that the consent given may be withdrawn at any time in a manner appropriate to its giving.

    All the documents should be send in the electronic form to the following address: praca@uwr.edu.pl with the message title: „assistant professor (post-doc) 116ZChBWB”.

    Additional information:

  • The University of Wroclaw reserves the right to contact only selected candidates.
  • Selected candidates may be required to undergo an interview by means of electronic communication allowing audio and video transmission.
  • The University of Wroclaw reserves the right to close the competition without selecting a candidate.
  • The University of Wroclaw reserves the right to cancel the competition.
  • The University of Wroclaw does not provide housing.
  • Information clause for persons participating in the recruitment process:

    Pursuant to Article 13 of Regulation 2016/679 of the European Parliament and of the Council of the European Union of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data and repealing Directive 95/46/EC (General Data Protection Regulation, RODO), we inform you that:

  • The administrator of your personal data is the University of Wroclaw based in Wroclaw, pl. Uniwersytecki 1, 50-137 Wroclaw, hereinafter referred to as the Administrator.
  • The Data Protection Officer at the University of Wroclaw is dr Krzysztof Ziemba, email address: iod@uwr.edu.pl
  • Your personal data will be processed for the purpose of recruitment to work at the University of Wroclaw. The legal basis for processing your personal data is Article 22 section1 of the Polish Labour Code, Article 119 of the Higher Education and Science Act and your consent.
  • Your personal data will not be made available to other recipients, with the exception of entities with which the controller has entered into appropriate agreements for the entrustment of processing and cases provided for by law.
  • Your data will be stored for the duration of the recruitment process, not longer than 12 months from the date of your application.
  • You have the right to:

  • withdraw consent to the processing of personal data, without affecting the lawfulness of processing carried out on the basis of consent before its withdrawal,

  • demand from the Administrator access to their personal data, rectification, erasure or restriction of processing of personal data, data portability, however these rights may be restricted by a specific legal provision,
  • make a complaint to the supervisory authority – the President of the Office for Personal Data Protection.

  • Providing personal data is voluntary, however, failure to provide data such as: first name(s) and surname, date of birth, place of residence (correspondence address), will result in inability to participate in the recruitment process.

  • Additional comments

    More about the employer:

    The University of Wrocław is among the largest and bests Polish universities, teaching more than 250 thousand students and employing about 2000 scientists (https: // uni.wroc.pl/en/). Wrocław city is a large, open and continuously developing city well communicated (airport, railways) with the world (https: // www. wroclaw.pl/en/).

    Contact Information
  • Organisation/Company: University of Wroclaw
  • Department: Faculty of Biotechnology
  • Organisation Type: Higher Education Institute
  • Website: https:// www. uni.wroc.pl
  • E-Mail: praca@uwr.edu.pl
  • Country: Poland
  • City: 50-137 Wrocław
  • Street: pl. Uniwersytecki 1
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