Assistant Professor of Molecular Immunology at LEO Foundation Skin Immunology Research Center (SIC)

Copenhagen University
July 14, 2024
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Assistant Professor of Molecular Immunology at LEO Foundation Skin Immunology Research Center (SIC), Department of Immunology and Microbiology, Faculty of Health and Medical Sciences

University of Copenhagen

We are looking for a highly motivated and dynamic assistant professor who has extensive experience in molecular immunology for a 3 year position to commence 1 October 2024.

You will undertake research that focusses on the role of the ubiquitin machinery in immune regulation and inflammation using genetically modified mouse models and cells derived from the animals. You will be expected to supervise junior group members and to participate in teaching activities

Information on the department can be found at: https: // isim.ku.dk/research/

Our research

We aim to uncover novel molecular mechanisms that regulate inflammation and immune responses. Through this, we aim to advance our understanding of the molecular aetiology of inflammatory skin diseases and other immune disorders.

A central focus of our research is to elucidate the role and regulation of the ubiquitin system, which plays a central role in regulating inflammation and immune responses in the skin and other organs/tissues. The ubiquitin system is an emerging drug target and through detailed studies of the molecular mechanisms underpinning ubiquitin-based immune signalling, we aim to identify “druggable” molecular processes that ultimately may have clinical benefit in the treatment of skin diseases and other immune-driven pathologies.

We believe in teamwork and have an inclusive and supportive working environment in an international, open-minded atmosphere with a diversity of nationalities among group members and at the Department at large.

Your job

You will undertake research that focusses on the role of the ubiquitin machinery in regulating the immune system at a cellular levels and at the level of intracellular molecular signalling processes, and how these mechanisms impinge on acute and chronic inflammation. The project involves extensive characterisation of genetically modified mice and the use of experimental models to trigger immune-related pathologies such as skin inflammation and colitis.

The long-term goal of the group's research is to identify molecular processes that underlie immune-driven pathologies and that can be targeted pharmacologically for treatment of skin diseases.

You will have documented experience in cellular and molecular immunology, experimental mouse models, generation of genetically modified mice, signal transduction, and ubiquitin biology, and will have hands-on experience with a wide range of experimental methodologies including but not limited to experimental mouse model systems, advanced flow cytometry, RNA sequencing, confocal microscopy, basic and advanced biochemical, molecular, and cell biology techniques.

The assistant professor's responsibilities will primarily consist of:

  • research, including publication/academic dissemination duties
  • research-based teaching
  • sharing knowledge with society
  • participation in formal pedagogical training programme for assistant professors
  • Profile Six overall criteria apply for assistant professor appointments at the University of Copenhagen. The six criteria (research, teaching, societal impact, organisational contribution, external funding, and leadership) are considered a framework for the overall assessment of candidates. Find information about each criterion here:https: // employment.ku.dk/faculty/criteria-for-recognising-merit.

    Furthermore, we are looking for a highly motivated and enthusiastic scientist with the following skills and experience:

    Essential experience and skills:

  • You have a PhD in Immunology
  • You are highly experienced in mouse cellular and molecular immunology, immune receptor signalling, molecular and biochemical techniques.
  • You have first-author and co-author publications in respected scientific journals
  • You have postgraduate teaching experience within immunology
  • Proficient communication skills and ability to work in teams
  • Excellent English skills written and spoken
  • Desirable experience and skills:

  • Experience in ubiquitin-based immune signalling
  • Experience in molecular biology and biochemical techniques
  • Experience in immune cell isolation, characterization and manipulation.
  • Knowledge of immunological mechanisms underlying chronic inflammatory diseases, e.g. psoriasis, inflammatory bowel disease
  • Place of employment

    The place of employment is at the LEO Foundation Skin Immunology Research Center (SIC), Department of Immunology and Microbiology, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and access to state-of-the-art core facilities for flow cytometry, single cell sequencing, proteomics, imaging, animal housing and transgenics.

    Terms of employment

    The average weekly working hours are 37 hours per week.

    The position is a fixed-term position limited to a period of 3 years. The start date is 1st October 2024.

    Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 38,575 DKK/approx. 5,100 EUR (April 2024 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

    Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years.

    The position is covered by the Job Structure for Academic Staff at Universities 2020.

    Questions For further information please contact Mads Gyrd-Hansen; [email protected] ; www. sund.ku.dk

    Foreign applicants may find this link useful: www. ism.ku.dk (International Staff Mobility).

    Application procedure Your application must be submitted in English by clicking ‘Apply now' below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Motivated letter of application (Max. one page)
  • CV incl. education, work/research experience, language skills and other skills relevant for the position
  • A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do
  • List of publications
  • Teaching portfolio (If applicable)
  • Deadline for applications: 14 July 2024 , 23.59pm CET

    We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

    The further process After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

    You can read about the recruitment process at https: // employment.ku.dk/faculty/recruitment-process/

    The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

    Interviews are expected to be held in week 33

    The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.

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