Assistant Professor of Bioinformatics in Epigenomic Research at The Novo Nordisk Foundation Center for Basic Metabolic Research

Copenhagen University
December 01, 2022
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Faculty of Health and Medical Sciences

University of Copenhagen

We are seeking a highly skilled bioinformatician to establish and run pipelines and to deliver analytical outputs. The position is for 3 years and to commence April 1, 2023.

About us

The Novo Nordisk Foundation Center for Basic Metabolic Research's vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge towards new prevention and treatment strategies. We were established in 2010, and in 2017, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower www. maersktower.ku.dk.

The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www. cbmr.ku.dk.

Our research

The position will be in the lab group of Professor Romain Barrès, which is part of the GECKO Consortium (Gametic Epigenetics Consortium against Obesity). This consortium, funded by a NNF Challenge Grant, aims to understand the cellular mechanisms by which environmentally-acquired epigenetic information transferred by spermatozoa to offspring can influence their development and predispose them to obesity. The GECKO Consortium is an international group of researchers from the University of Copenhagen, the University of Sydney and the University of Chicago, giving many opportunities for collaboration and insight from a variety of experts.

Your job

We are seeking a skilled and experienced bioinformatician to perform bioinformatic comparative analyses of the responses to nutritional stress across species. In particular, DNA methylation and small non-coding RNA expression in spermatozoa will be assessed using next-generation sequencing. The applicant is expected to work and consult with colleagues concerning issues of data analysis and interpretation. Additionally, the applicant is expected to formulate hypotheses, initiate projects, and manage them through to completion. Candidates with additional background in mathematical modelling, machine learning and molecular biology would be highly regarded.

The assistant professor's responsibilities will primarily consist of:

  • research, including publication/academic dissemination duties
  • research-based teaching
  • sharing knowledge with society
  • participation in formal pedagogical training program for assistant professors
  • Profile

    We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience: Essential criteria

  • PhD in Bioinformatics, Computational Biology or related field.
  • Expert knowledge in epigenetic mechanisms, DNA methylation and small RNA biology.
  • High level of proficiency in programming and experience in applying statistical methods to genomic data (preferably in R and/or Python).
  • Solid experience in Linux/UNIX environment, shell scripting and high- performance computing (HPC).
  • Expertise in next generation sequencing (NGS) data analysis such as RNA- seq, Bisulfite-seq (WGBS, RRBS), ChIP-seq).
  • Experience with circadian data analysis (rhythmicity and differential rhythmicity)
  • Experience in the management and handling of large-scale genomic data.
  • Knowledge in Git and demonstrated capacity for collaborative and reactive programming.
  • Knowledge of human physiology and metabolic disorders
  • Experience in supervising other researchers at different levels.
  • Demonstrated capacity for effective teamwork.
  • Proven track record showing scientific productivity in peer-reviewed journals.
  • Excellent English communication skills, both written and oral.
  • Place of employment

    The place of employment is the Novo Nordisk Foundation Center for Basic Metabolic Research, Maersk Tower, Faculty of Health and Medical Sciences, University of Copenhagen. We offer stimulating working conditions in a dynamic and international research environment

    Terms of employment

    The employment as assistant professor is a full time and fixed-term position for 3 years. Starting date is April 1, 2023.

    Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations). The monthly salary will be based on the number of years of work experience (seniority) with the possibility to negotiate a salary supplement based on prior experiences and qualifications.

    Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

    The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

    Questions For further information please contact Professor Romain Barrès at barres@sund.ku.dk. For questions regarding the recruitment procedure, please contact SUND HR CBMR at SUND-HR-CBMR@sund.ku.dk.

    Foreign applicants may find this link useful: www. ism.ku.dk (International Staff Mobility).

    Application procedure Your online application must be submitted in English by clicking ‘Apply now' below. Furthermore, your application must include the following documents/attachments – all in PDF format:

    1. Motivated letter of application (max. one page)

    2. CV incl. education, work/research experience, language skills and other skills relevant for the position

    3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate

    4. List of publications

    5. Teaching portfolio if applicable

    Application deadline: 1 December 2022 , 23.59pm CET

    We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

    The further process After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

    You can read about the recruitment process at https: // employment.ku.dk/faculty/recruitment-process/

    The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

    The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

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