1-2 Postdoctoral Fellows In Structure And Function Of Gpcr Signaling Complexes

Göteborg University

Sweden

February 1, 2022

Description

The University of Gothenburg tackles society's challenges with diverse knowledge. 53 500 students and 6 500 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:

  • The Department of Infectious Diseases
  • The Department of Microbiology and Immunology
  • The Department of Medical Biochemistry and Cell Biology
  • The Department of Laboratory Medicine
  • At present, the institute has about 360 employees and approximately 450 million SEK in total assets.

    We are currently seeking several highly talented, innovative and results- driven persons for postdoctoral positions in structure and function of GPCR signaling complexes in the Johansson laboratory at the Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine at the Göteborg University, Sweden.

    Subject area

    Structure and function of GPCR signaling complexes.

    Subject area description

    G protein-coupled receptors (GPCRs) are key transmembrane proteins that serve to transduce external stimuli to signals across the membrane and they constitute about 30-40% of all therapeutic drug targets. GPCRs are inherently allosteric and interact via distinct domains with both endogenous and synthetic compounds, proteins, metabolites, hormones and small molecules. Methodological breakthroughs have accelerated structure determination of GPCRs, however our understanding of the molecular basis of signaling complexes remain elusive. We will characterize these complexes using structural, biophysical and pharmacological methods.

    Job assignments

    The successful candidates will work on the structure and function of select GPCR signaling complexes using a combination of structural, biochemical and pharmacological approaches. The candidates will be encouraged and expected to conduct their research independently and to plan and execute research tasks in a timely manner. The candidates are also expected to travel for data collection purposes and to participate in collaborations with other research groups (either within Sweden or abroad). Additionally, the candidates may also be asked to assist in supervision of Masters or doctoral students.

    Eligibility

    An achieved doctoral degree is compulsory for a position as postdoctor at the University of Gothenburg. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.

    The qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

    Assessment

    The applicants must have a PhD in a relevant area of research (such as structural biology, biochemistry/biophysics, pharmacology or related fields). The successful candidates should have extensive experience in cloning, (membrane) protein expression (in mammalian cells) and extra merit is given to those with previous experience in structural biology (cryo-EM or X-ray crystallography) or in GPCR pharmacology.

    Great emphasis will be placed on the candidate's personal suitability for the position and interest in the subject area as well as their long-term research goals. The work involves close collaborations with other researchers and thus demands flexibility and a willingness to travel for data collection purposes. Excellent communication skills (spoken and written) in English are a prerequisite for the position.

    Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

    Employment

    The employment is full time and temporary, 2 years with the possibility of 1 year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

    For further information:

    Please contact: Linda Johansson; email: linda.johansson.4@gu.se ; telephone: +46(0)766183244.

    Unions

    Union representatives at the University of Gothenburg: https: // www. gu.se/en/about-the-university/work-at-the-university-of- gothenburg/how-to-apply

    Information for International Applicants

    Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

    https: // www. gu.se/en/about-the-university/welcome-services https: // www. movetogothenburg.com/

    How to apply

    In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

    The application should contain:

    - A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

    - A CV including a list of publications

    - Proof of completed PhD

    - Contact details of two references

    Closing date : 2022-02-01

    The University of Gothenburg promotes equal opportunities, equality and diversity.

    Salary is determined on an individual basis.

    Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

    In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

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